Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6435004 | 1.00 | SRD5A2 (0.47) | SRD5A2SRD5A1OPRM1OPRK1OPRL1 | |
| SCHEMBL6431907 | 1.00 | SRD5A2 (0.47) | SRD5A2SRD5A1OPRM1OPRK1OPRL1 | |
| SCHEMBL6431812 | 0.80 | SRD5A2 (0.42) | SRD5A2SRD5A1 | |
| SCHEMBL6434024 | 0.72 | SRD5A1 (0.35) | SRD5A2SRD5A1 | |
| SCHEMBL6430872 | 0.71 | SRD5A2 (0.46) | SRD5A2SRD5A1 | |
| SCHEMBL6435587 | 0.68 | SRD5A1 (0.39) | SRD5A1 | |
| SCHEMBL6432312 | 0.67 | OPRM1 (0.33) | OPRM1OPRK1OPRL1 | |
| SCHEMBL6431337 | 0.63 | SRD5A2 (0.39) | SRD5A2SRD5A1 | |
| SCHEMBL2114822 | 0.63 | CTDSP1 (0.49) | SRD5A2SRD5A1 | |
| SCHEMBL11086770 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066284-B1 | BENZO(C)QUINOLIZINE DERIVATIVES AND THEIR USE AS 5 ALPHA-REDUCTASES INHIBITORS | APPLIED RESEARCH SYSTEMS (AN) | 2005-08-31 | — | — | EP | claimed |
| US-6962925-B1 | Benzo(C)quinolizine derivatives and their use as 5α-reductases inhibitors | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2005-11-08 | — | — | US | disclosed |
| EP-1066284-B1 | BENZO(C)QUINOLIZINE DERIVATIVES AND THEIR USE AS 5 ALPHA-REDUCTASES INHIBITORS | APPLIED RESEARCH SYSTEMS (AN) | 2005-08-31 | — | — | EP | disclosed |