Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.59 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | BCL2 | P10415 | 1/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | USP5 | P45974 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CCKBR | P32239 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7894669 | 0.92 | MAPK9 (0.59) | MAPK9MAPK10KMT2AMEN1ALDH1A1 | |
| SCHEMBL2420177 | 0.90 | MAPK9 (0.60) | MAPK9MAPK10KMT2AMEN1ALDH1A1 | |
| SCHEMBL2428799 | 0.88 | MAPK9 (0.61) | MAPK9MAPK10KMT2AMEN1ALDH1A1 | |
| SCHEMBL2423054 | 0.87 | MAPK9 (0.59) | MAPK9MAPK10KMT2AMEN1ALDH1A1 | |
| SCHEMBL7894689 | 0.87 | MAPK9 (0.55) | MAPK9MAPK10KMT2AMEN1ALDH1A1 | |
| SCHEMBL2424777 | 0.87 | MAPK9 (0.57) | MAPK9MAPK10KMT2AMEN1ALDH1A1 | |
| SCHEMBL7894704 | 0.87 | MAPK9 (0.55) | MAPK9MAPK10KMT2AMEN1ALDH1A1 | |
| SCHEMBL2424858 | 0.87 | MAPK9 (0.61) | MAPK9MAPK10KMT2AMEN1ALDH1A1 | |
| SCHEMBL27493937 | 0.86 | MAPK9 (0.54) | MAPK9MAPK10KMT2AMEN1ALDH1A1 | |
| SCHEMBL2425870 | 0.86 | MAPK9 (0.60) | MAPK9MAPK10KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218374-B1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | APPLIED RESEARCH SYSTEMS (AN) | 2005-11-16 | — | — | EP | claimed |