Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.59 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 5/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CCKBR | P32239 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2420177 | 0.96 | MAPK9 (0.60) | MAPK9MAPK10MAPTMEN1KMT2A | |
| SCHEMBL7894689 | 0.95 | MAPK9 (0.55) | MAPK9MAPK10MAPTMEN1KMT2A | |
| SCHEMBL7894704 | 0.95 | MAPK9 (0.55) | MAPK9MAPK10MAPTMEN1KMT2A | |
| SCHEMBL2425275 | 0.93 | MAPK9 (0.53) | MAPK9MAPK10MAPTMEN1KMT2A | |
| SCHEMBL3479895 | 0.92 | MAPK9 (0.53) | MAPK9MAPK10MAPTMEN1KMT2A | |
| SCHEMBL2422619 | 0.92 | MAPK9 (0.52) | MAPK9MAPK10MAPTMEN1KMT2A | |
| SCHEMBL6431701 | 0.92 | MAPK9 (0.59) | MAPK9MAPK10MAPTMEN1KMT2A | |
| SCHEMBL2424777 | 0.91 | MAPK9 (0.57) | MAPK9MAPK10MAPTMEN1KMT2A | |
| SCHEMBL27493937 | 0.90 | MAPK9 (0.54) | MAPK9MAPK10MAPTMEN1KMT2A | |
| SCHEMBL7435815 | 0.90 | MAPK9 (0.55) | MAPK9MAPK10MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1088821-A1 | Pharmaceutically active sulfonamide derivatives | Applied Research Systems ARS Holding N.V. (AN) | 2001-04-04 | — | — | EP | claimed |
| EP-1088821-A1 | Pharmaceutically active sulfonamide derivatives | Applied Research Systems ARS Holding N.V. (AN) | 2001-04-04 | — | — | EP | disclosed |