Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 20/20 | 1.00 |
| ▸ | ABCC8 | Q09428 | 20/20 | 1.00 |
| ▸ | KCNJ11 | Q14654 | 20/20 | 1.00 |
| ▸ | KCNJ8 | Q15842 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7235036 | 0.91 | ABCC9 (0.83) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL7232279 | 0.91 | ABCC9 (0.83) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL7234610 | 0.88 | ABCC9 (0.79) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL7235496 | 0.86 | ABCC9 (0.76) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL7241954 | 0.86 | ABCC9 (0.75) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL7243266 | 0.85 | ABCC9 (0.75) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL7231969 | 0.85 | ABCC9 (1.00) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL7233146 | 0.85 | ABCC9 (0.74) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL7234820 | 0.85 | ABCC9 (0.73) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL7141004 | 0.84 | ABCC9 (0.76) | ABCC9ABCC8KCNJ11KCNJ8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194429-B1 | POTASSIUM CHANNEL OPENERS | ABBOTT LAB (US) | 2005-03-30 | — | — | EP | disclosed |