Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL29149666 | 0.96 | ALDH1A1 (0.47) | ALDH1A1MAPK1RAB9ANPC1LMNA | |
| Lithium Ion SCHEMBL138828 | 0.96 | ALDH1A1 (0.47) | ALDH1A1MAPK1RAB9ANPC1LMNA | |
| Iodide SCHEMBL702154 | 0.93 | ALDH1A1 (0.44) | ALDH1A1MAPK1RAB9ANPC1LMNA | |
| Iodide SCHEMBL701438 | 0.93 | ALDH1A1 (0.44) | ALDH1A1MAPK1RAB9ANPC1LMNA | |
| SCHEMBL11707018 | 0.93 | ALDH1A1 (0.50) | ALDH1A1MAPK1RAB9ANPC1LMNA | |
| Benzene SCHEMBL31091106 | 0.93 | ALDH1A1 (0.50) | ALDH1A1MAPK1RAB9ANPC1LMNA | |
| SCHEMBL143876 | 0.93 | ALDH1A1 (0.50) | ALDH1A1MAPK1RAB9ANPC1LMNA | |
| SCHEMBL404594 | 0.89 | ALDH1A1 (0.47) | ALDH1A1MAPK1RAB9ANPC1LMNA | |
| Ammonia Solution, Strong SCHEMBL234555 | 0.89 | ALDH1A1 (0.47) | ALDH1A1MAPK1RAB9ANPC1LMNA | |
| Potassium Ion SCHEMBL134847 | 0.89 | ALDH1A1 (0.47) | ALDH1A1MAPK1RAB9ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1536539-A1 | RAPID CHARGING BATTERY CHARGING SYSTEM | Nisshinbo Industries, Inc. (JP) | 2005-06-01 | — | — | EP | disclosed |