Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 9/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.36 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10417520 | 0.74 | ADRA2A (0.57) | CYP19A1SLC22A12IMPDH2IMPDH1 | |
| SCHEMBL1249225 | 0.74 | ADRA2A (0.53) | CNR2 | |
| Hydrochloric Acid SCHEMBL1508039 | 0.73 | ADRA2A (0.59) | CYP19A1SLC22A12IMPDH2IMPDH1 | |
| SCHEMBL3096449 | 0.72 | CYP19A1 (0.51) | CYP19A1SLC22A12IMPDH2IMPDH1AR | |
| SCHEMBL24337996 | 0.69 | CYP19A1 (0.51) | CYP19A1SLC22A12IMPDH2IMPDH1AR | |
| SCHEMBL29559252 | 0.69 | CYP19A1 (0.51) | CYP19A1SLC22A12IMPDH2IMPDH1AR | |
| SCHEMBL8156604 | 0.69 | ADRA2A (0.47) | — | |
| SCHEMBL12017482 | 0.68 | SLC6A4 (0.41) | — | |
| SCHEMBL2462113 | 0.68 | CYP19A1 (0.50) | CYP19A1SLC22A12IMPDH2IMPDH1AR | |
| SCHEMBL3078346 | 0.68 | CYP19A1 (0.50) | CYP19A1SLC22A12IMPDH2IMPDH1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492515-A1 | PHARMACEUTICAL COMPOSITION COMPRISING AN AROMATASE INHIBITOR AND AN ESTROGEN SUITABLE FOR HORMONE REPLACEMENT THERAPY FOR A MALE | JENCAP RESEARCH LTD. (CA) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003082254-A1 | PHARMACEUTICAL COMPOSITION COMPRISING AN AROMATASE INHIBITOR AND AN ESTROGEN SUITABLE FOR HORMONE REPLACEMENT THERAPY FOR A MALE | JENCAP RESEARCH LTD. (CA) | 2003-10-09 | — | — | WO | disclosed |