Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTBP2 | P56545 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20816048 | 0.82 | SMN1; SMN2 (0.55) | ALDH1A1SMN1; SMN2HIF1A | |
| SCHEMBL28417924 | 0.80 | CTBP2 (0.43) | CTBP2FFAR1HTTGAAGRM2 | |
| SCHEMBL27513458 | 0.78 | GAA (0.43) | CTBP2FFAR1HTTGAAGRM2 | |
| SCHEMBL4764876 | 0.77 | HPGD (0.45) | CTBP2FFAR1HTTGAAGRM2 | |
| SCHEMBL28553221 | 0.76 | CTBP2 (0.43) | CTBP2FFAR1HTTGAAGRM2 | |
| SCHEMBL23430239 | 0.74 | HPGD (0.46) | CTBP2FFAR1HTTGAAHPGD | |
| SCHEMBL5390491 | 0.74 | SMN1; SMN2 (0.68) | CTBP2FFAR1HTTGAAGRM2 | |
| SCHEMBL5394972 | 0.74 | PPARG (0.49) | CTBP2FFAR1HTTGAAHPGD | |
| SCHEMBL8740577 | 0.74 | KDM4E (0.45) | CTBP2FFAR1HTTALDH1A1HPGD | |
| SCHEMBL9079628 | 0.72 | BLM (0.71) | CTBP2GAAGRM2GRM3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329457-B1 | Antipicornaviral compounds, their preparation and use | AGOURON PHARMA (US) | 2005-11-02 | — | — | EP | disclosed |