Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.44 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5343038 | 0.84 | BLM (0.56) | CTBP2BLMALDH1A1LMNAHTT | |
| SCHEMBL9724009 | 0.84 | FDPS (0.46) | KDM4ETDP1POLBAPEX1HPGD | |
| SCHEMBL7908936 | 0.83 | SMN1; SMN2 (0.52) | KDM4ERIPK1PPARAPPARGALDH1A1 | |
| SCHEMBL687447 | 0.83 | SMN1; SMN2 (0.52) | KDM4ERIPK1PPARAPPARGALDH1A1 | |
| SCHEMBL7908766 | 0.83 | SMN1; SMN2 (0.52) | KDM4ERIPK1PPARAPPARGALDH1A1 | |
| SCHEMBL2241052 | 0.79 | LDHA (0.49) | KDM4ECTBP2FFAR1POLBALDH1A1 | |
| SCHEMBL4764876 | 0.78 | HPGD (0.45) | KDM4ERIPK1CTBP2TDP1FFAR1 | |
| SCHEMBL28417924 | 0.77 | CTBP2 (0.43) | KDM4ECTBP2FFAR1POLBHPGD | |
| SCHEMBL5160750 | 0.77 | CYP2C19 (0.48) | TDP1POLBALDH1A1 | |
| SCHEMBL10029122 | 0.77 | ALDH1A1 (0.41) | KDM4ECTBP2TDP1FFAR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748220-A4 | METHODS AND COMPOSITIONS FOR TREATING ANDROGEN-DEPENDENT DISEASES USING OPTICALLY PURE R-(-)-CASODEX | SEPRACOR INC (US) | 1997-09-10 | — | — | EP | disclosed |
| EP-0748220-A1 | METHODS AND COMPOSITIONS FOR TREATING ANDROGEN-DEPENDENT DISEASES USING OPTICALLY PURE R-(-)-CASODEX | SEPRACOR, INC. (US) | 1996-12-18 | — | — | EP | disclosed |
| WO-1995019770-A1 | METHODS AND COMPOSITIONS FOR TREATING ANDROGEN-DEPENDENT DISEASES USING OPTICALLY PURE R-(-)-CASODEX | SEPRACOR, INC. (US) | 1995-07-27 | — | — | WO | disclosed |