Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.50 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8067078 | 0.95 | ANPEP (0.50) | ANPEPERAP1ERAP2CYP2A6HTR2A | |
| SCHEMBL855071 | 0.95 | ANPEP (0.50) | ANPEPERAP1ERAP2CYP2A6HTR2A | |
| SCHEMBL5924988 | 0.95 | ANPEP (0.50) | ANPEPERAP1ERAP2CYP2A6HTR2A | |
| Hydrochloric Acid SCHEMBL9635016 | 0.93 | ANPEP (0.48) | ANPEPERAP1ERAP2CYP2A6HTR2A | |
| SCHEMBL27549431 | 0.90 | ADRA1A (0.51) | ANPEPERAP1ERAP2HTR2AKCNH2 | |
| SCHEMBL8242110 | 0.86 | TACR1 (0.47) | TAAR1ACP3MAOBKCNH2ALDH1A1 | |
| SCHEMBL3604156 | 0.86 | TACR1 (0.47) | TAAR1ACP3MAOBKCNH2ALDH1A1 | |
| SCHEMBL20725551 | 0.85 | ANPEP (0.46) | ANPEPERAP1ERAP2CYP2A6HTR2A | |
| Hydrochloric Acid SCHEMBL2321850 | 0.84 | TACR1 (0.46) | TAAR1ACP3MAOBKCNH2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2321848 | 0.84 | TACR1 (0.46) | TAAR1ACP3MAOBKCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1411927-A4 | METHOD FOR THE PREPARATION OF SELECTIVELY-SUBSTITUTED CORROLES AND NEW SUBSTITUTED CORROLES | TECHNION RES & DEV FOUNDATION (IL) | 2005-04-20 | — | — | EP | disclosed |
| EP-1411927-A1 | METHOD FOR THE PREPARATION OF SELECTIVELY-SUBSTITUTED CORROLES AND NEW SUBSTITUTED CORROLES | Technion Research and Development Foundation Ltd. (IL) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003004021-A1 | METHOD FOR THE PREPARATION OF SELECTIVELY-SUBSTITUTED CORROLES AND NEW SUBSTITUTED CORROLES | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2003-01-16 | — | — | WO | disclosed |