Methacrylic Acid

Methacrylic Acid

SCHEMBL6432802

C=C(C)C(=O)O.C=C(C)C(=O)O.C=C(C)C(=O)O.C=C(C)C(=O)O.CC(O)(O)C(O)O

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 5/20 0.43
ALDH1A1 P00352 2/20 0.36
TSHR P16473 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
TET3 O43151 1/20 0.31
TET1 Q8NFU7 1/20 0.31
HMGCR P04035 1/20 0.31
CHRM1 P11229 1/20 0.31
TBXA2R P21731 1/20 0.31
ADRA1A P35348 1/20 0.31
TP53 P04637 1/20 0.30
HPGD P15428 1/20 0.30
TGFBR1 P36897 1/20 0.30
FFAR3 O14843 1/20 0.30
LCK P06239 1/20 0.30
FYN P06241 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL27947566 0.87 TET2 (0.41) TET2ALDH1A1TSHRTDP1TET3
Methacrylic Acid SCHEMBL3802187 0.86 TET2 (0.39) TET2ALDH1A1TSHRTDP1HMGCR
Methacrylic Acid SCHEMBL372922 0.86 TET2 (0.39) TET2ALDH1A1TSHRTDP1TET3
Methacrylic Acid SCHEMBL28318482 0.83 ALDH1A1 (0.44) TET2ALDH1A1TSHRTDP1HMGCR
Methacrylic Acid SCHEMBL10488480 0.83 ALDH1A1 (0.44) TET2ALDH1A1TSHRTDP1HMGCR
Methacrylic Acid SCHEMBL14686495 0.83 ALDH1A1 (0.44) TET2ALDH1A1TSHRTDP1HMGCR
Methacrylic Acid SCHEMBL6856806 0.83 ALDH1A1 (0.44) TET2ALDH1A1TSHRTDP1HMGCR
Methacrylic Acid SCHEMBL28401998 0.82 TET2 (0.41) TET2ALDH1A1TSHRTDP1TET3
Methacrylic Acid SCHEMBL27698778 0.82 TET2 (0.41) TET2ALDH1A1TSHRTDP1TET3
Methacrylic Acid SCHEMBL27586025 0.80 TET2 (0.42) TET2ALDH1A1TSHRTDP1HMGCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1326901-B1 ACYLPHOSPHINE OXIDE PHOTOINITIATORS IN METHACRYLATE CASTING RESINS CIBA SC HOLDING AG (CH) 2005-06-08 EP disclosed
US-20030164580-A1 Acylphosphine oxide photoinitiators in methacrylate casting resins CIBA SPECIALTY CHEMICALS CORP. 2003-09-04 US disclosed
EP-1326901-A1 ACYLPHOSPHINE OXIDE PHOTOINITIATORS IN METHACRYLATE CASTING RESINS Ciba SC Holding AG (CH) 2003-07-16 EP disclosed
WO-2002022697-A1 ACYLPHOSPHINE OXIDE PHOTOINITIATORS IN METHACRYLATE CASTING RESINS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-03-21 WO disclosed