Pefurazoate

Pefurazoate

SCHEMBL6433092

C=CCCCOC(=O)C(CC)N(Cc1ccco1)C(=O)n1ccnc1.CC1=C(C(=O)Nc2ccccc2)S(=O)(=O)CCO1

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
MAPT P10636 2/20 0.32
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
ALDH1A1 P00352 3/20 0.30
LMNA P02545 2/20 0.30
KDM4E B2RXH2 1/20 0.30
HPGD P15428 1/20 0.30
HTT P42858 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
MEN1 O00255 1/20 0.30
POLB P06746 1/20 0.30
PKM P14618 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pefurazoate SCHEMBL20067 0.83 MAPT (0.35) TSHRMAPTCYP1A2CYP3A4CYP2C9
(R)-(+)-Pefurazoate SCHEMBL8163178 0.83 MAPT (0.35) TSHRMAPTCYP1A2CYP3A4CYP2C9
Pefurazoate SCHEMBL28205047 0.83
Pefurazoate SCHEMBL27797684 0.82 MAPT (0.35) TSHRMAPTCYP1A2CYP3A4CYP2C9
Pefurazoate SCHEMBL28180407 0.79 MAPT (0.32) TSHRMAPTCYP1A2CYP3A4CYP2C9
Pefurazoate SCHEMBL28269053 0.77 POLB (0.33) TSHRMAPTCYP1A2CYP3A4CYP2C9
Pefurazoate SCHEMBL5264939 0.72 MEN1 (0.31) HTTNPSR1MEN1KMT2A
SCHEMBL28641743 0.72 TSHR (0.36) TSHRMAPTCYP1A2CYP3A4CYP2C9
SCHEMBL19186469 0.70 MAPT (0.34) TSHRMAPTCYP1A2CYP3A4CYP2C9
Pefurazoate SCHEMBL28785223 0.70 MEN1 (0.45) MAPTMEN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1596657-A2 FUNGICIDE COMPOSITION COMPRISING FENAMIDONE AND HYMEXAZOL Bayer CropScience S.A. (FR) 2005-11-23 EP disclosed
WO-2004073401-A2 FUNGICIDE COMPOSITION COMPRISING FENAMIDONE AND HYMEXAZOL BAYER CROPSCIENCE SA (FR) 2004-09-02 WO disclosed