Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6474117 | 0.81 | GRIK1 (0.47) | GRIK1GRIK2EPHX1CES2CES1 | |
| SCHEMBL5698394 | 0.81 | GRIK1 (0.47) | GRIK1GRIK2EPHX1CES2CES1 | |
| SCHEMBL5698392 | 0.81 | GRIK1 (0.47) | GRIK1GRIK2EPHX1CES2CES1 | |
| SCHEMBL6474115 | 0.81 | GRIK1 (0.47) | GRIK1GRIK2EPHX1CES2CES1 | |
| SCHEMBL17077032 | 0.79 | GRIK1 (0.42) | GRIK1GRIK2EPHX1CES2CES1 | |
| SCHEMBL17077033 | 0.79 | GRIK1 (0.42) | GRIK1GRIK2EPHX1CES2CES1 | |
| SCHEMBL585162 | 0.76 | GRIK1 (0.40) | GRIK1GRIK2EPHX1CES2CES1 | |
| SCHEMBL7671245 | 0.76 | GRIK1 (0.40) | GRIK1GRIK2EPHX1CES2CES1 | |
| SCHEMBL6666614 | 0.76 | CES2 (0.42) | GRIK1GRIK2EPHX1CES2CES1 | |
| SCHEMBL4086059 | 0.76 | GRIK1 (0.40) | GRIK1GRIK2EPHX1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1591462-A2 | Temperature-responsive polymer compound and process for producing the same | Amersham Biosciences KK (JP) | 2005-11-02 | — | — | EP | disclosed |
| US-20050224415-A1 | Temperature-responsive polymer compound and process for producing the same | AMERSHAM BIOSCIENCES KK | 2005-10-13 | — | — | US | disclosed |
| EP-1153049-A1 | TEMPERATURE-RESPONSIVE POLYMER COMPOUND AND PROCESS FOR PRODUCING THE SAME | Amersham Pharmacia Biotech K.K. (JP) | 2001-11-14 | — | — | EP | disclosed |
| WO-2000044800-A1 | TEMPERATURE-RESPONSIVE POLYMER COMPOUND AND PROCESS FOR PRODUCING THE SAME | AMERSHAM PHARMACIA BIOTECH K.K. (JP) | 2000-08-03 | — | — | WO | disclosed |