Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.50 |
| ▸ | DRD3 | P35462 | 3/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | HTR2B | P41595 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | STAT6 | P42226 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6360387 | 0.85 | GAA (0.57) | HPGDGAAMAPTLMNASMN1; SMN2 | |
| SCHEMBL12438392 | 0.83 | ALDH1A1 (0.60) | HPGDALDH1A1KDM4EGAALMNA | |
| SCHEMBL1134956 | 0.83 | ALDH1A1 (0.60) | HPGDALDH1A1KDM4EGAALMNA | |
| SCHEMBL12438414 | 0.83 | ALDH1A1 (0.60) | HPGDALDH1A1KDM4EGAALMNA | |
| SCHEMBL23136224 | 0.82 | GAA (0.60) | HPGDGAAMAPTLMNASMN1; SMN2 | |
| SCHEMBL1134981 | 0.82 | ALDH1A1 (0.60) | HPGDALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL8286971 | 0.81 | GAA (0.56) | HPGDGAAMAPTLMNASMN1; SMN2 | |
| SCHEMBL11733379 | 0.80 | CYP2D6 (0.48) | HPGDALDH1A1KDM4ELMNACYP2D6 | |
| SCHEMBL1753441 | 0.79 | GAA (0.54) | HPGDGAAMAPTLMNASMN1; SMN2 | |
| SCHEMBL10073072 | 0.78 | KMT2A (0.63) | GAAMAPTKMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1009402-A1 | COMPOSITIONS AND USE OF BENZAMIDES AND NICOTINAMIDES AS ANTI-INFLAMMATORY AGENTS | OXIGENE, INC. (US) | 2000-06-21 | — | — | EP | claimed |
| EP-1009402-A4 | COMPOSITIONS AND USE OF BENZAMIDES AND NICOTINAMIDES AS ANTI-INFLAMMATORY AGENTS | OXIGENE INC (US) | 2000-06-21 | — | — | EP | claimed |
| US-6028111-A | Compositions and use of benzamides and nicotinamides as anti-inflammatory agents | OXIGENE, INC. (US) | 2000-02-22 | — | — | US | claimed |
| WO-1997032582-A1 | COMPOSITIONS AND USE OF BENZAMIDES AND NICOTINAMIDES AS ANTI-INFLAMMATORY AGENTS | OXIGENE, INC. (US) | 1997-09-12 | — | — | WO | claimed |
| EP-1009402-B1 | COMPOSITIONS AND USE OF BENZAMIDES AS ANTI-INFLAMMATORY AGENTS | OXIGENE INC (US) | 2005-07-27 | — | — | EP | disclosed |
| EP-1083890-A4 | N-ACETYL 3-CHLOROPROCAINAMIDE, ACID ADDITION SALTS THEREOF, AND METHODS OF USE | OXIGENE INC (US) | 2002-04-24 | — | — | EP | disclosed |
| EP-1083890-A1 | N-ACETYL 3-CHLOROPROCAINAMIDE, ACID ADDITION SALTS THEREOF, AND METHODS OF USE | Oxigene, Inc. (US) | 2001-03-21 | — | — | EP | disclosed |
| US-6100299-A | N-acetyl 3-chloroprocainamide, acid addition salts thereof, and methods of use | OXIGENE, INC. (US) | 2000-08-08 | — | — | US | disclosed |
| EP-1009402-A1 | COMPOSITIONS AND USE OF BENZAMIDES AND NICOTINAMIDES AS ANTI-INFLAMMATORY AGENTS | OXIGENE, INC. (US) | 2000-06-21 | — | — | EP | disclosed |
| EP-1009402-A4 | COMPOSITIONS AND USE OF BENZAMIDES AND NICOTINAMIDES AS ANTI-INFLAMMATORY AGENTS | OXIGENE INC (US) | 2000-06-21 | — | — | EP | disclosed |
| US-6028111-A | Compositions and use of benzamides and nicotinamides as anti-inflammatory agents | OXIGENE, INC. (US) | 2000-02-22 | — | — | US | disclosed |
| WO-1999063987-A1 | N-ACETYL 3-CHLOROPROCAINAMIDE, ACID ADDITION SALTS THEREOF, AND METHODS OF USE | OXIGENE, INC. (US) | 1999-12-16 | — | — | WO | disclosed |
| WO-1997032582-A1 | COMPOSITIONS AND USE OF BENZAMIDES AND NICOTINAMIDES AS ANTI-INFLAMMATORY AGENTS | OXIGENE, INC. (US) | 1997-09-12 | — | — | WO | disclosed |