Ethylene Glycol

Ethylene Glycol

SCHEMBL6433273

CCCCCCCCCCCCCCCCCC(=O)OCC(C)OC(=O)CCCCCCCCCCCCCCCCC.OCCO

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.66
ALDH1A1 P00352 1/20 0.66
PRKCA P17252 4/20 0.65
PRKCE Q02156 2/20 0.65
PRKCQ Q04759 2/20 0.65
PRKCD Q05655 2/20 0.65
MAPT P10636 2/20 0.63
KDM4E B2RXH2 1/20 0.59
DUSP3 P51452 1/20 0.59
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
MAPK1 P28482 1/20 0.56
LPAR1 Q92633 2/20 0.54
LPAR3 Q9UBY5 2/20 0.54
ENPP2 Q13822 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL16457 1.00 LMNA (0.66) LMNAALDH1A1PRKCAPRKCEPRKCQ
Ethylene Glycol SCHEMBL180497 1.00 LMNA (0.66) LMNAALDH1A1PRKCAPRKCEPRKCQ
Ethylene Glycol SCHEMBL56526 1.00 LMNA (0.66) LMNAALDH1A1PRKCAPRKCEPRKCQ
Ethylene Glycol SCHEMBL2115585 1.00 LMNA (0.66) LMNAALDH1A1PRKCAPRKCEPRKCQ
Ethylene Glycol SCHEMBL629793 1.00 LMNA (0.66) LMNAALDH1A1PRKCAPRKCEPRKCQ
Ethylene Glycol SCHEMBL1173235 1.00 LMNA (0.66) LMNAALDH1A1PRKCAPRKCEPRKCQ
Ethylene Glycol SCHEMBL141667 1.00 LMNA (0.66) LMNAALDH1A1PRKCAPRKCEPRKCQ
Ethylene Glycol SCHEMBL9160363 0.98 LMNA (0.64) LMNAALDH1A1PRKCAPRKCEPRKCQ
Ethylene Glycol SCHEMBL12489211 0.98 LMNA (0.63) LMNAALDH1A1PRKCAPRKCEPRKCQ
Butane SCHEMBL3900185 0.97 LMNA (0.61) LMNAALDH1A1PRKCAPRKCEPRKCQ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1556022-A1 AQUEOUS 2,6-DIISOPROPYLPHENOL PHARMACEUTICAL COMPOSITIONS Transform Pharmaceuticals, Inc. (US) 2005-07-27 EP claimed
EP-1539122-A2 AQUEOUS 2,6-DIISOPROPYLPHENOL PHARMACEUTICAL COMPOSITIONS Transform Pharmaceuticals, Inc. (US) 2005-06-15 EP claimed
US-20050027019-A1 Aqueous 2,6-diisopropylphenol pharmaceutical compositions JANSSEN BIOTECH, INC. 2005-02-03 US claimed
US-20040220283-A1 Aqueous 2,6-diisopropylphenol pharmaceutical compositions TRANSFORM PHARMACEUTICALS, INC. (US) 2004-11-04 US claimed
WO-2004039360-A1 AQUEOUS 2,6-DIISOPROPYLPHENOL PHARMACEUTICAL COMPOSITIONS TRANSFORM PHARMACEUTICALS, INC. (US) 2004-05-13 WO claimed
WO-2004010941-A2 AQUEOUS 2,6-DIISOPROPYLPHENOL PHARMACEUTICAL COMPOSITIONS TRANSFORM PHARMACEUTICALS, INC. (US) 2004-02-05 WO claimed
US-4151274-A Process and composition for the production of suppositories Karl-Werner Schlueter G.m.b.H. (DE) 1979-04-24 US claimed
WO-2020255865-A1 TOPICAL COMPOSITION 小林製薬株式会社 2020-12-24 WO disclosed
WO-1998048768-A9 COMPOSITIONS FOR COSMETIC APPLICATIONS MEDLOGIC GLOBAL CORP (US) 1999-03-25 WO disclosed
US-4151274-A Process and composition for the production of suppositories Karl-Werner Schlueter G.m.b.H. (DE) 1979-04-24 US disclosed