Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.74 |
| ▸ | CCR2 | P41597 | 2/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | BUB1 | O43683 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6433060 | 0.86 | F10 (0.71) | F10CCR2HPGDS | |
| SCHEMBL6433340 | 0.85 | F10 (0.85) | F10CCR2 | |
| SCHEMBL6436677 | 0.83 | F10 (0.59) | F10CCR2MTNR1AMTNR1BROCK2 | |
| SCHEMBL6433546 | 0.81 | CCR2 (0.67) | F10CCR2MTNR1AMTNR1BGRIN1 | |
| SCHEMBL6433700 | 0.80 | CCR2 (0.54) | F10CCR2MTNR1AMTNR1BGRIN1 | |
| SCHEMBL6433022 | 0.78 | F10 (0.65) | F10CCR2MTNR1AMTNR1B | |
| SCHEMBL6432886 | 0.77 | F10 (0.56) | F10CCR2 | |
| SCHEMBL6435685 | 0.76 | F10 (0.71) | F10CCR2MTNR1AMTNR1B | |
| SCHEMBL6440151 | 0.75 | F10 (0.72) | F10CCR2MTNR1AMTNR1B | |
| SCHEMBL6432347 | 0.74 | F10 (0.61) | F10CCR2MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042287-B1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | AVENTIS PHARMA GMBH (DE) | 2005-04-20 | — | — | EP | disclosed |
| US-6337344-B1 | ANTICOAGULANTS AND ENZYME INHIBITORS FOR CARDIOVASCULAR DISORDERS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-01-08 | — | — | US | disclosed |