SCHEMBL6433581

SCHEMBL6433581

OCC(O)[CH]CC(O)CO

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.44
ALDH1A1 P00352 1/20 0.44
AKR1B1 P15121 1/20 0.41
THRB P10828 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7860724 0.74
SCHEMBL6433484 0.74
SCHEMBL9117457 0.74
SCHEMBL5307339 0.72 LMNA (0.40) LMNAALDH1A1AKR1B1THRB
SCHEMBL5307337 0.72 LMNA (0.40) LMNAALDH1A1AKR1B1THRB
SCHEMBL3674773 0.71
SCHEMBL1231853 0.69
SCHEMBL7129909 0.69
SCHEMBL7129912 0.69
SCHEMBL6436031 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220390458-A1 FLUORESCENT PROBE AND APPLICATIONS THEREOF CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2022-12-08 US disclosed
EP-3795643-A1 FLUORESCENT PROBE AND APPLICATIONS THEREOF Centre National de la Recherche Scientifique (FR) 2021-03-24 EP disclosed
EP-1172400-B1 THERMOPLASTIC RESIN FILM WITH SATISFACTORY PRINTABILITY YUPO CORP (JP) 2005-12-28 EP disclosed
US-6586106-B2 Ink transfer, adhesion and aging stability, and being satisfactory in back ghost when offset printing using oxidation polymerization type ink is performed on both faces YUPO CORPORATION (JP) 2003-07-01 US disclosed
US-20020054991-A1 Thermoplastic resin film satisfactory in printability YUPO CORPORATION (JP) 2002-05-09 US disclosed
EP-1172400-A1 THERMOPLASTIC RESIN FILM WITH SATISFACTORY PRINTABILITY Yupo Corporation (JP) 2002-01-16 EP disclosed
US-5981579-A TREATING OR CONTROLLING A DISEASE OR STRESS CONDITION SUCH AS LAMINITIS IN A NON-HUMAN MAMMAL BY TOPICALLY APPLYING TO THE LIMB OF THE MAMMAL A NITROVASODILATOR AND A PROTECTIVE COVERING DRESSING IN THE FORM OF A CUFF, SLEEVE, OR BOOT THE UNIVERSITY OF SHEFFIELD (GB) 1999-11-09 US disclosed
EP-0019843-B1 SISOMICIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINES BAYER AG (DE) 1982-09-29 EP disclosed
US-4312859-A ANTIBIOTICS, BACTERICIDES BAYER AKTIENGESELLSCHAFT (DE) 1982-01-26 US disclosed
EP-0019843-A1 Sisomicin derivatives, process for their preparation and their use as medicines BAYER AG (DE) 1980-12-10 EP disclosed