Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.38 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 4/20 | 0.36 |
| ▸ | TET3 | O43151 | 1/20 | 0.36 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| E968 SCHEMBL27092634 | 1.00 | TGFBR1 (0.43) | TGFBR1PDE4ALMNAUSP2SLCO1B1 | |
| E968 SCHEMBL4778196 | 1.00 | TGFBR1 (0.43) | TGFBR1PDE4ALMNAUSP2SLCO1B1 | |
| E968 SCHEMBL9847628 | 1.00 | TGFBR1 (0.43) | TGFBR1PDE4ALMNAUSP2SLCO1B1 | |
| E968 SCHEMBL18784099 | 1.00 | TGFBR1 (0.43) | TGFBR1PDE4ALMNAUSP2SLCO1B1 | |
| E968 SCHEMBL960729 | 1.00 | TGFBR1 (0.43) | TGFBR1PDE4ALMNAUSP2SLCO1B1 | |
| E968 SCHEMBL3651326 | 1.00 | TGFBR1 (0.43) | TGFBR1PDE4ALMNAUSP2SLCO1B1 | |
| E968 SCHEMBL2152820 | 1.00 | TGFBR1 (0.43) | TGFBR1PDE4ALMNAUSP2SLCO1B1 | |
| E968 SCHEMBL7107678 | 1.00 | TGFBR1 (0.43) | TGFBR1PDE4ALMNAUSP2SLCO1B1 | |
| Mannitol SCHEMBL22418765 | 0.90 | PDE4A (0.54) | TGFBR1PDE4ALMNAUSP2SLCO1B1 | |
| Mannitol SCHEMBL28482880 | 0.90 | PDE4A (0.54) | TGFBR1PDE4ALMNAUSP2SLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3924437-A1 | RESIN COMPOSITIONS AND METHODS OF PRODUCTION | Momentive Performance Materials Inc. (US) | 2021-12-22 | — | — | EP | disclosed |
| WO-2020167507-A1 | RESIN COMPOSITIONS AND METHODS OF PRODUCTION | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2020-08-20 | — | — | WO | disclosed |
| EP-1326901-B1 | ACYLPHOSPHINE OXIDE PHOTOINITIATORS IN METHACRYLATE CASTING RESINS | CIBA SC HOLDING AG (CH) | 2005-06-08 | — | — | EP | disclosed |
| US-20030164580-A1 | Acylphosphine oxide photoinitiators in methacrylate casting resins | CIBA SPECIALTY CHEMICALS CORP. | 2003-09-04 | — | — | US | disclosed |