Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 7/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28084645 | 0.83 | ALOX15 (0.44) | ALOX15MGAMGAASIMGAM2 | |
| SCHEMBL6436094 | 0.79 | HMGCR (0.54) | ALOX15HIF1ACYP3A4ALDH1A1TSHR | |
| SCHEMBL1734711 | 0.79 | ALOX15 (0.37) | ALOX15MGAMGAASIMGAM2 | |
| SCHEMBL3763202 | 0.79 | ALOX15 (0.38) | ALOX15HIF1AEPAS1CYP3A4LMNA | |
| SCHEMBL12746064 | 0.78 | ALOX15 (0.40) | ALOX15HIF1AEPAS1 | |
| SCHEMBL7047649 | 0.76 | HMGCR (0.50) | MGAMGAASIMGAM2LMNA | |
| SCHEMBL9946195 | 0.75 | HSD17B10 (0.39) | MGAMGAASIMGAM2LMNA | |
| SCHEMBL10892827 | 0.75 | TSHR (0.39) | MGAMGAASIMGAM2LMNA | |
| SCHEMBL1736059 | 0.74 | ALOX15 (0.37) | ALOX15MGAMGAASIMGAM2 | |
| SCHEMBL10767936 | 0.73 | TSHR (0.37) | MGAMGAASIMGAM2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104803853-B | Anti-Vibrio vulnificus monoterpene derivative, and preparation method and application thereof | 中国科学院海洋研究所 | 2017-02-22 | — | — | CN | claimed |
| US-RE45128-E1 | Cephalotaxane derivatives and their processes of preparation and purification | IVAX International GmbH (CH) | 2014-09-09 | — | — | US | disclosed |
| US-7842687-B2 | Natural, synthetic or semi-synthetic crude harringtonines purified by chromatography and crystallization in which the solvent is water or lower C1-4 alkanol or an aqueous mixture of organic solvents; treatment of cancer through oral administration | CHEMGENEX PHARMACEUTICALS, INC. (AU) | 2010-11-30 | — | — | US | disclosed |
| US-7169774-B2 | Cephalotaxane derivatives and their processes of preparation and purification | STRAGEN PHARMA S.A. (CH) | 2007-01-30 | — | — | US | disclosed |
| EP-1109798-B1 | GERANIC ACID DERIVATIVES | FIRMENICH & CIE (CH) | 2005-10-12 | — | — | EP | disclosed |
| US-6384242-B1 | 4-METHYL-4-(4-METHYLPENT-3-EN-1-YL)-2-OXETANONE; ITS SYNTHESIS FROM 6-METHYL-5-HEPTEN-2-ONE AND KETENE; INTERMEDIATE FOR 3-HYDROXYCITRONELLIC ESTERS AND 2,6-DIMETHYLHEPTADIENE/1,5-/ UPON PYROLYSIS | FIRMENICH SA (CH) | 2002-05-07 | — | — | US | disclosed |
| EP-1109798-A1 | GERANIC ACID DERIVATIVES | FIRMENICH SA (CH) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000014080-A1 | GERANIC ACID DERIVATIVES | FIRMENICH S.A. (CH) | 2000-03-16 | — | — | WO | disclosed |