Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 2/20 | 0.40 |
| ▸ | HTR1B | P28222 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6434408 | 0.83 | ROR1 (0.35) | PTGDR2MEN1KMT2A | |
| SCHEMBL10323522 | 0.82 | PTGDR2 (0.53) | PTGDR2HTR1DHTR1BADRA1AADRA1D | |
| SCHEMBL7208759 | 0.74 | PTGDR2 (0.44) | PTGDR2HTR1DHTR1BADRA1AADRA1D | |
| SCHEMBL824116 | 0.68 | HTR2C (0.53) | ADRA1AADRA1DUSP2DRD2MEN1 | |
| SCHEMBL34463201 | 0.68 | HTR2C (0.53) | ADRA1AADRA1DUSP2DRD2MEN1 | |
| SCHEMBL6433011 | 0.68 | ROR1 (0.39) | PTGDR2MEN1KMT2A | |
| SCHEMBL4753995 | 0.67 | ALDH1A1 (0.41) | ADRA1AADRA1DHTR1ADRD3DRD2 | |
| SCHEMBL21821532 | 0.67 | CA1 (0.46) | KMT2ASIGMAR1 | |
| SCHEMBL7209700 | 0.67 | HTR1D (0.42) | PTGDR2HTR1DHTR1BADRA1AADRA1D | |
| SCHEMBL10632525 | 0.66 | PTGDR2 (0.59) | PTGDR2HTR1DHTR1BADRA1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165495-B1 | RESORCINOL DERIVATIVES | PFIZER (US) | 2005-04-20 | — | — | EP | disclosed |