Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.81 |
| ▸ | F2 | P00734 | 3/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6435208 | 0.94 | F10 (0.71) | F10F2FOLH1ALDH1A1GAA | |
| SCHEMBL6433741 | 0.86 | F10 (0.61) | F10F2 | |
| Trifluoroacetic Acid SCHEMBL6434438 | 0.83 | F10 (0.87) | F10F2 | |
| SCHEMBL6432965 | 0.80 | F10 (0.66) | F10ALDH1A1GAAMAPTPKM | |
| SCHEMBL14809872 | 0.76 | F10 (0.61) | F10ALDH1A1GAAMAPTPKM | |
| SCHEMBL6432971 | 0.74 | F10 (0.58) | F10FOLH1ALDH1A1GAAMAPT | |
| SCHEMBL6432583 | 0.74 | F10 (0.58) | F10FOLH1ALDH1A1GAAMAPT | |
| SCHEMBL27560061 | 0.73 | F10 (0.55) | F10F2FOLH1 | |
| SCHEMBL28742466 | 0.73 | F10 (0.47) | F10F2 | |
| SCHEMBL5955785 | 0.71 | FOLH1 (0.59) | F10F2FOLH1MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042287-B1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | AVENTIS PHARMA GMBH (DE) | 2005-04-20 | — | — | EP | disclosed |
| US-6337344-B1 | ANTICOAGULANTS AND ENZYME INHIBITORS FOR CARDIOVASCULAR DISORDERS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-01-08 | — | — | US | disclosed |
| EP-1042287-A1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | Aventis Pharma Deutschland GmbH (DE) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033800-A1 | INDOLE DERIVATIVES AS INHIBITORS OR FACTOR XA | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 1999-07-08 | — | — | WO | disclosed |