Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.58 |
| ▸ | CCR2 | P41597 | 4/20 | 0.50 |
| ▸ | FEN1 | P39748 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | EDNRB | P24530 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | KLK1 | P06870 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6432965 | 0.94 | F10 (0.66) | F10CCR2FEN1ARALDH1A1 | |
| SCHEMBL6432583 | 0.92 | F10 (0.58) | F10CCR2FEN1ARALDH1A1 | |
| SCHEMBL6436700 | 0.81 | F10 (0.51) | F10CCR2FEN1GAAMAPT | |
| SCHEMBL6435208 | 0.80 | F10 (0.71) | F10CCR2ALDH1A1GAAMAPT | |
| SCHEMBL6434382 | 0.80 | F10 (0.51) | F10ALDH1A1MAPTPKMKLKB1 | |
| SCHEMBL13011271 | 0.80 | ROCK2 (0.51) | F10CCR2ARKLKB1KLK1 | |
| SCHEMBL6437062 | 0.76 | POLB (0.49) | F10CCR2GAAMAPTPKM | |
| SCHEMBL6433700 | 0.76 | CCR2 (0.54) | F10CCR2ALDH1A1MAPT | |
| SCHEMBL6436902 | 0.75 | F10 (0.47) | F10CCR2FEN1ALDH1A1KLKB1 | |
| SCHEMBL13062044 | 0.75 | CCR2 (0.51) | CCR2FEN1ALDH1A1FOLH1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042287-B1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | AVENTIS PHARMA GMBH (DE) | 2005-04-20 | — | — | EP | disclosed |
| US-6337344-B1 | ANTICOAGULANTS AND ENZYME INHIBITORS FOR CARDIOVASCULAR DISORDERS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-01-08 | — | — | US | disclosed |