SCHEMBL6435972

SCHEMBL6435972

O=C1CCCC(c2ccc(OCc3ccccc3)cc2O)C1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
HPD P32754 1/20 0.46
MAOB P27338 5/20 0.45
MAOA P21397 3/20 0.45
NPC1 O15118 1/20 0.44
ALDH1A1 P00352 1/20 0.44
HPGD P15428 1/20 0.44
NFKB1 P19838 1/20 0.44
GRM5 P41594 1/20 0.44
RAB9A P51151 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
CA2 P00918 1/20 0.43
CA5A P35218 1/20 0.43
CREBBP Q92793 1/20 0.43
CYP4F2 P78329 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11165591 0.88 MAOB (0.45) CYP2C19CYP3A4CYP2C9HPDMAOB
SCHEMBL11165828 0.88 MAOB (0.44) CYP2C19CYP3A4CYP2C9MAOBMAOA
SCHEMBL11170404 0.87 MAOB (0.43) MAOBMAOAGRIN1GRIN2B
SCHEMBL6434537 0.84 CA2 (0.42) CYP2C19HPDMAOBALDH1A1CA2
SCHEMBL9419127 0.83 GRIN1 (0.48) CYP2C19CYP3A4CYP2C9HPDMAOB
SCHEMBL3542422 0.81 CYP3A4 (0.48) CYP2C19CYP3A4CYP2C9MAOBMAOA
SCHEMBL11172493 0.81 CYP3A4 (0.36) CYP2C19CYP3A4CYP2C9MAOBMAOA
SCHEMBL6434946 0.80 PDE10A (0.41) CYP3A4NPC1ALDH1A1HPGDRAB9A
SCHEMBL11170400 0.79 CYP3A4 (0.41) CYP2C19CYP3A4CYP2C9GRIN1GRIN2B
SCHEMBL11158749 0.79 PTPN1 (0.46) NPC1ALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1165495-B1 RESORCINOL DERIVATIVES PFIZER (US) 2005-04-20 EP claimed