⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4311855 | 0.73 | — | — | |
| SCHEMBL6436203 | 0.71 | — | — | |
| SCHEMBL6437610 | 0.71 | — | — | |
| SCHEMBL1140792 | 0.69 | — | — | |
| SCHEMBL10523283 | 0.67 | — | — | |
| SCHEMBL11433455 | 0.67 | — | — | |
| SCHEMBL6437728 | 0.65 | — | — | |
| SCHEMBL10520258 | 0.64 | — | — | |
| SCHEMBL910847 | 0.63 | — | — | |
| SCHEMBL1079368 | 0.62 | ALDH1A1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36187-E | HERPES SIMPLEX VIRUS; HUMAN CYTOMEGALOVIRUS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1999-04-06 | — | — | US | claimed |
| US-4968686-A | DECREASED CYTOTOXICITY; CYTOMEGALO AND HERPEX SIMPLEX VIRUSES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1990-11-06 | — | — | US | claimed |
| EP-1097720-B1 | Antiviral agent in combination with radiation therapy for use in treatment of cancer | ROUSSY INST GUSTAVE (FR) | 2005-10-12 | — | — | EP | disclosed |
| US-20040192637-A1 | Antiviral agent for use in treatment of cancer | INSTITUT GUSTAVE ROUSSY (FR) | 2004-09-30 | — | — | US | disclosed |
| US-6723712-B2 | Antiviral agent for use in treatment of cancer | INSTITUT GUSTAVE ROUSSY (FR) | 2004-04-20 | — | — | US | disclosed |
| EP-1246623-A4 | COMPOUNDS SPECIFIC TO ADENOSINE A1, A2A, AND A3 RECEPTOR AND USES THEREOF | OSI PHARM INC (US) | 2003-05-14 | — | — | EP | disclosed |
| US-20020193339-A1 | Antiviral agent for use in treatment of cancer | INSTITUT GUSTAVE ROUSSY (FR) | 2002-12-19 | — | — | US | disclosed |
| EP-1246623-A1 | COMPOUNDS SPECIFIC TO ADENOSINE A1, A2A, AND A3 RECEPTOR AND USES THEREOF | OSI Pharmaceuticals, Inc. (US) | 2002-10-09 | — | — | EP | disclosed |
| EP-1237576-A1 | ANTIVIRAL AGENT FOR USE IN TREATMENT OF CANCER | INSTITUT GUSTAVE ROUSSY (FR) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001039777-A1 | COMPOUNDS SPECIFIC TO ADENOSINE A1 A2A, AND A3 RECEPTORS AND USES THEREOF | OSI PHARMACEUTICALS, INC. (US) | 2001-06-07 | — | — | WO | disclosed |
| WO-2001032215-A1 | ANTIVIRAL AGENT FOR USE IN TREATMENT OF CANCER | INSTITUT GUSTAVE ROUSSY (FR) | 2001-05-10 | — | — | WO | disclosed |
| US-5386030-A | Chemical intermediates | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCE OF THE CZECH REPUBLIC (CZ) | 1995-01-31 | — | — | US | disclosed |
| EP-0574386-A1 | NOVEL PROCESS FOR THE PREPARATION OF NUCLEOTIDES | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1993-12-22 | — | — | EP | disclosed |
| EP-0574386-A4 | NOVEL PROCESS FOR THE PREPARATION OF NUCLEOTIDES. | BRISTOL MYERS SQUIBB CO (US) | 1993-10-27 | — | — | EP | disclosed |
| US-5208221-A | Nucleotides and intermediates for herpes virus or leukemia virus | BRISTOL-MYERS SQUIBB COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| EP-0494370-A1 | Antiviral (phosphonomethoxy)methoxy purine/pyrimidine derivatives | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) | 1992-07-15 | — | — | EP | disclosed |
| WO-1992002511-A1 | NOVEL PROCESS FOR THE PREPARATION OF NUCLEOTIDES | BRISTOL-MYERS SQUIBB COMPANY (US) | 1992-02-20 | — | — | WO | disclosed |
| EP-0454427-A1 | Antiretroviral bases | Institute of Organic Chemistry and Biochemistry of the Academy of Sciences of the Czech Republic (CZ) | 1991-10-30 | — | — | EP | disclosed |
| US-4968686-A | DECREASED CYTOTOXICITY; CYTOMEGALO AND HERPEX SIMPLEX VIRUSES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1990-11-06 | — | — | US | disclosed |
| US-4927830-A | HERPES, CYTOMEGALO VIRUS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1990-05-22 | — | — | US | disclosed |