SCHEMBL643673

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL642567	0.89	GCK (0.59)	GCKSMN1; SMN2RAB9AHTTKCNH2
	SCHEMBL644079	0.88	GCK (0.51)	GCKKDM4ESMN1; SMN2RAB9AHTT
	SCHEMBL643599	0.87	GCK (0.65)	GCKKDM4ESMN1; SMN2RAB9AKCNH2
	SCHEMBL643823	0.87	GCK (0.78)	GCKKCNH2
	SCHEMBL644648	0.85	GCK (0.63)	GCKKCNH2
	SCHEMBL644367	0.85	GCK (0.57)	GCKKCNH2
	SCHEMBL643421	0.85	GCK (0.56)	GCKKCNH2
	SCHEMBL644871	0.85	GCK (0.57)	GCKKCNH2
	SCHEMBL643703	0.83	GCK (0.53)	GCKSMN1; SMN2RAB9ALMNAMAPT
	SCHEMBL644377	0.83	GCK (0.52)	GCKKDM4ESMN1; SMN2HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.