⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10843079 | 0.78 | — | — | |
| SCHEMBL9036256 | 0.75 | — | — | |
| SCHEMBL363516 | 0.69 | — | — | |
| SCHEMBL11501524 | 0.69 | — | — | |
| SCHEMBL7029942 | 0.67 | — | — | |
| SCHEMBL7087520 | 0.67 | — | — | |
| SCHEMBL20594365 | 0.65 | — | — | |
| SCHEMBL308453 | 0.64 | — | — | |
| SCHEMBL20594216 | 0.61 | — | — | |
| SCHEMBL34390 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1463511-A4 | COMBINATION CANCER THERAPY | PHARMACYCLICS INC (US) | 2005-09-28 | — | — | EP | disclosed |
| EP-1463511-A1 | COMBINATION CANCER THERAPY | PHARMACYCLICS, INC. (US) | 2004-10-06 | — | — | EP | disclosed |
| WO-2003049743-A1 | COMBINATION CANCER THERAPY | PHARMACYCLICS, INC. (US) | 2003-06-19 | — | — | WO | disclosed |