SCHEMBL6437091

SCHEMBL6437091

CC(C)OC(=O)C(N)CCCCN

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.53
GNAI3 P08754 1/20 0.42
GNAO1 P09471 1/20 0.42
GNAI1 P63096 1/20 0.42
CPB2 Q96IY4 3/20 0.41
DPP7 Q9UHL4 8/20 0.40
DPP8 Q6V1X1 4/20 0.40
DPP9 Q86TI2 4/20 0.40
RNPEP Q9H4A4 1/20 0.38
DPP4 P27487 2/20 0.38
TLR2 O60603 2/20 0.36
FAP Q12884 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1603054 1.00 GSR (0.53) GSRGNAI3GNAO1GNAI1CPB2
Hydrochloric Acid SCHEMBL28125330 0.98 GSR (0.52) GSRGNAI3GNAO1GNAI1CPB2
Hydrochloric Acid SCHEMBL28125331 0.98 GSR (0.52) GSRGNAI3GNAO1GNAI1CPB2
SCHEMBL8778639 0.94 GSR (0.45) GSRGNAI3GNAO1GNAI1CPB2
SCHEMBL8778638 0.94 GSR (0.45) GSRGNAI3GNAO1GNAI1CPB2
SCHEMBL1003010 0.89 GSR (0.53) GSRGNAI3GNAO1GNAI1CPB2
SCHEMBL22494143 0.87 GSR (0.52) GSRGNAI3GNAO1GNAI1CPB2
Hydrochloric Acid SCHEMBL21802388 0.87 GSR (0.52) GSRGNAI3GNAO1GNAI1CPB2
Hydrochloric Acid SCHEMBL6704964 0.87 GSR (0.52) GSRGNAI3GNAO1GNAI1CPB2
SCHEMBL23457451 0.84 GSR (0.57) GSRGNAI3GNAO1GNAI1CPB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104603145-B β-hairpin peptidomimetics 波利弗尔股份公司 2018-05-18 CN claimed
CN-104603145-A Beta-hairpin peptidomimetics POLYPHOR AG 2015-05-06 CN claimed
CN-103703018-A Beta-hairpin peptidomimetics as CXC4 antagonists POLYPHOR AG 2014-04-02 CN claimed
EP-1603549-A2 IMPROVED BIOAVAILABILITY AND IMPROVED DELIVERY OF ACIDIC PHARMACEUTICAL DRUGS Yu, Ruey J., Dr. (US) 2005-12-14 EP claimed
US-20040220264-A1 Bioavailability and improved delivery of acidic pharmaceutical drugs YU RUEY J 2004-11-04 US claimed
WO-2004082628-A2 IMPROVED BIOAVAILABILITY AND IMPROVED DELIVERY OF ACIDIC PHARMACEUTICAL DRUGS YU RUEY J (US) 2004-09-30 WO claimed
WO-2023235929-A1 FUNCTIONALISED BENZOPYRAN COMPOUNDS AND USES THEREOF NOXOPHARM LIMITED (AU) 2023-12-14 WO disclosed
EP-4282867-A1 INDOLINE-CONTAINING SPIRO DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN MEDICINE Changchun Genescience Pharmaceutical Co., Ltd. (CN) 2023-11-29 EP disclosed
EP-3668867-B1 SYNTHESIS, PHARMACOLOGY AND USE OF NEW AND SELECTIVE FMS-LIKE TYROSINE KINASE 3 (FLT3) FLT3 INHIBITORS UNIV REGENSBURG (DE) 2023-10-04 EP disclosed
CN-115073327-B Method for preparing glutarimide by using urea as carbonylation agent 中国科学院过程工程研究所 2023-05-30 CN disclosed
CN-115073327-A Method for preparing pentanedicarbamate by using urea as carbonylation agent 中国科学院过程工程研究所 2022-09-20 CN disclosed
US-11384076-B2 Synthesis, pharmacology and use of new and selective FMS-like tyrosine kinase 3 (FLT3) FLT3 inhibitors UNIVERSITÄT REGENSBURG (DE) 2022-07-12 US disclosed
US-20200190075-A1 SYNTHESIS, PHARMACOLOGY AND USE OF NEW AND SELECTIVE FMS-LIKE TYROSINE KINASE 3 (FLT3) FLT3 INHIBITORS UNIVERSITÄT REGENSBURG (DE) 2020-06-18 US disclosed
US-20040220264-A1 Bioavailability and improved delivery of acidic pharmaceutical drugs YU RUEY J 2004-11-04 US disclosed
WO-2004082628-A2 IMPROVED BIOAVAILABILITY AND IMPROVED DELIVERY OF ACIDIC PHARMACEUTICAL DRUGS YU RUEY J (US) 2004-09-30 WO disclosed
EP-1135398-A1 CYANOPHOSPHONAMIDES AND METHOD FOR PREPARATION Monsanto Technology LLC (US) 2001-09-26 EP disclosed
US-6218563-B1 Cyanophosphonamides and method for preparation MONSANTO COMPANY 2001-04-17 US disclosed
WO-2000032611-A1 CYANOPHOSPHONAMIDES AND METHOD FOR PREPARATION MONSANTO TECHNOLOGY LLC (US) 2000-06-08 WO disclosed
US-4163034-A DECYCLIZATION, ESTERIFICATION; FIREPROOFING HOECHST AG. (DE) 1979-07-31 US disclosed
US-4096208-A FIREPROOFING AGENTS HOECHST AKTIENGESELLSCHAFT (DT) 1978-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11384076-B2 Synthesis, pharmacology and use of new and selective FMS-like tyrosine kinase 3 (FLT3) FLT3 inhibitors FLT3, CSF3R, ABL1 GSR 2905/4885GNAI3 992/4885GNAO1 2191/4885
US-20200190075-A1 SYNTHESIS, PHARMACOLOGY AND USE OF NEW AND SELECTIVE FMS-LIKE TYROSINE KINASE 3 (FLT3) FLT3 INHIBITORS FLT3, CSF3R, ABL1 GSR 2905/4885GNAI3 992/4885GNAO1 2191/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.