Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.34 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8778639 | 1.00 | GSR (0.45) | GSRDPP7DPP4DPP8DPP9 | |
| SCHEMBL6437091 | 0.94 | GSR (0.53) | GSRDPP7DPP4DPP8DPP9 | |
| SCHEMBL1603054 | 0.94 | GSR (0.53) | GSRDPP7DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL28125331 | 0.92 | GSR (0.52) | GSRDPP7DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL28125330 | 0.92 | GSR (0.52) | GSRDPP7DPP4DPP8DPP9 | |
| SCHEMBL1838293 | 0.84 | SLC15A1 (0.50) | DPP7DPP4DPP8DPP9SLC15A1 | |
| SCHEMBL28024261 | 0.84 | TSHR (0.34) | GSRDPP7CYP1A2TSHRSLC15A1 | |
| SCHEMBL1838292 | 0.84 | SLC15A1 (0.50) | DPP7DPP4DPP8DPP9SLC15A1 | |
| SCHEMBL19547632 | 0.83 | GSR (0.41) | GSRDPP7DPP4DPP8DPP9 | |
| SCHEMBL1003010 | 0.82 | GSR (0.53) | GSRDPP7DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804471-A1 | GNRH ANTAGONISTS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1997-11-05 | — | — | EP | disclosed |
| US-5506207-A | CONTRACEPTIVES, ANTITUMOR AGENTS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1996-04-09 | — | — | US | disclosed |
| WO-1995025741-A1 | GNRH ANTAGONISTS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1995-09-28 | — | — | WO | disclosed |
| WO-1994019370-A1 | GNRH ANTAGONISTS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1994-09-01 | — | — | WO | disclosed |