SCHEMBL6437280

SCHEMBL6437280

C=C(C)C(=O)OCCC(COC(=O)C(=C)C)(COC(=O)C(=C)C)COC(=O)C(=C)C

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.50
TSHR P16473 3/20 0.48
ALDH1A1 P00352 3/20 0.39
POLB P06746 1/20 0.37
APEX1 P27695 1/20 0.37
HTT P42858 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HIF1A Q16665 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19342611 0.91 THRB (0.50) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL13109797 0.91 THRB (0.46) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL26002227 0.90 THRB (0.55) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL57880 0.85 TSHR (0.52) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL2245821 0.84 TSHR (0.48) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL213774 0.84 THRB (0.50) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL9777906 0.84 TSHR (0.44) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL26002244 0.84 TSHR (0.53) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL16803285 0.83 TSHR (0.50) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL9007734 0.82 THRB (0.58) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4526920-A Contains poly(meth)acrylic ester of oxy or polyoxyalkane polyol, polymerization initiator, filler MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1985-07-02 US claimed
CN-109964152-B Formable antiglare polymer film 科思创德国股份有限公司 2021-12-28 CN disclosed
EP-1326901-B1 ACYLPHOSPHINE OXIDE PHOTOINITIATORS IN METHACRYLATE CASTING RESINS CIBA SC HOLDING AG (CH) 2005-06-08 EP disclosed
US-20030164580-A1 Acylphosphine oxide photoinitiators in methacrylate casting resins CIBA SPECIALTY CHEMICALS CORP. 2003-09-04 US disclosed
EP-1326901-A1 ACYLPHOSPHINE OXIDE PHOTOINITIATORS IN METHACRYLATE CASTING RESINS Ciba SC Holding AG (CH) 2003-07-16 EP disclosed
WO-2002022697-A1 ACYLPHOSPHINE OXIDE PHOTOINITIATORS IN METHACRYLATE CASTING RESINS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-03-21 WO disclosed
EP-0100688-B1 CURABLE COATING COMPOSITION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1987-04-22 EP disclosed
US-4526920-A Contains poly(meth)acrylic ester of oxy or polyoxyalkane polyol, polymerization initiator, filler MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1985-07-02 US disclosed
EP-0100688-A2 Curable coating composition MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1984-02-15 EP disclosed