Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SELL | P14151 | 1/20 | 0.38 |
| ▸ | SELP | P16109 | 1/20 | 0.38 |
| ▸ | SELE | P16581 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19249421 | 0.85 | TYR (0.48) | TYRRAB9AALDH1A1CES2MAPT | |
| Tetrabuthylammonium SCHEMBL7706138 | 0.83 | TYR (0.41) | TYRTSHRMAPTKDM4ETP53 | |
| SCHEMBL6437541 | 0.79 | TYR (0.49) | TYRALDH1A1CA12CA1CA2 | |
| SCHEMBL6437507 | 0.79 | TYR (0.49) | TYRALDH1A1CA12CA1CA2 | |
| SCHEMBL6435789 | 0.79 | TYR (0.49) | TYRALDH1A1CA12CA1CA2 | |
| SCHEMBL3164917 | 0.78 | ESR2 (0.53) | TYRRAB9AALDH1A1MAPTNPSR1 | |
| SCHEMBL6437210 | 0.78 | ESR2 (0.53) | TYRRAB9AALDH1A1MAPTNPSR1 | |
| SCHEMBL3162433 | 0.77 | ALDH1A1 (0.43) | TYRRAB9AALDH1A1MAPTGAA | |
| SCHEMBL29871375 | 0.77 | ALDH1A1 (0.43) | TYRRAB9AALDH1A1MAPTGAA | |
| Resorcinol SCHEMBL8654256 | 0.77 | CA12 (0.52) | NPC1RAB9AAKR1C3AKR1C1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165495-A1 | RESORCINOL DERIVATIVES | PFIZER INC. (US) | 2002-01-02 | — | — | EP | claimed |
| WO-2000056702-A1 | RESORCINOL DERIVATIVES | PFIZER INC. (US) | 2000-09-28 | — | — | WO | claimed |
| EP-1165495-B1 | RESORCINOL DERIVATIVES | PFIZER (US) | 2005-04-20 | — | — | EP | disclosed |
| EP-1165495-A1 | RESORCINOL DERIVATIVES | PFIZER INC. (US) | 2002-01-02 | — | — | EP | disclosed |
| EP-1134207-A1 | Process for preparing resorcinol derivatives | Pfizer Products Inc. (US) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000056702-A1 | RESORCINOL DERIVATIVES | PFIZER INC. (US) | 2000-09-28 | — | — | WO | disclosed |