Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6439899 | 0.86 | SLC6A2 (0.47) | ALOX5APFEN1SLC6A2SLC6A3HTR1A | |
| SCHEMBL6434537 | 0.84 | CA2 (0.42) | SLC6A2SLC6A3MAOBLIPGMEN1 | |
| SCHEMBL6433213 | 0.81 | ESR2 (0.46) | ESR2MAOAMAOBMEN1ALDH1A1 | |
| SCHEMBL6434372 | 0.76 | ESR2 (0.51) | ESR2MEN1ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL6434367 | 0.76 | ESR2 (0.51) | ESR2MEN1ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL6434539 | 0.76 | TYR (0.43) | ESR2BCHEACHECYP2C19 | |
| SCHEMBL11165591 | 0.72 | MAOB (0.45) | ALOX5APFEN1SLC6A2SLC6A3HTR1A | |
| SCHEMBL6435273 | 0.71 | PTPN1 (0.36) | ESR2KMT2A | |
| SCHEMBL6435274 | 0.71 | PTPN1 (0.36) | ESR2KMT2A | |
| SCHEMBL23036101 | 0.69 | SLC6A2 (0.56) | ALOX5APFEN1SLC6A2SLC6A3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165495-B1 | RESORCINOL DERIVATIVES | PFIZER (US) | 2005-04-20 | — | — | EP | disclosed |