SCHEMBL6437583

SCHEMBL6437583

CCCCNC(=O)NC(NC(=O)NCCCC)c1ccc(N(C)C)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.58
CNR2 P34972 7/20 0.53
HDAC3 O15379 4/20 0.49
HDAC1 Q13547 4/20 0.49
HDAC2 Q92769 4/20 0.49
HDAC8 Q9BY41 4/20 0.49
TSHR P16473 1/20 0.47
HDAC11 Q96DB2 4/20 0.45
HDAC4 P56524 3/20 0.45
HDAC7 Q8WUI4 3/20 0.45
HDAC10 Q969S8 3/20 0.45
HDAC6 Q9UBN7 3/20 0.45
HDAC9 Q9UKV0 3/20 0.45
HDAC5 Q9UQL6 3/20 0.45
EPHX1 P07099 2/20 0.44
GAA P10253 2/20 0.43
POLB P06746 1/20 0.43
NPC1 O15118 1/20 0.43
MAPT P10636 1/20 0.43
RAB9A P51151 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3154888 0.89 HDAC3 (0.49) ALDH1A1CNR2HDAC3HDAC1HDAC2
SCHEMBL6440486 0.82 EPHX1 (0.49) ALDH1A1CNR2HDAC3HDAC1HDAC2
SCHEMBL6438903 0.82 EPHX2 (0.56) ALDH1A1CNR2TSHREPHX1POLB
SCHEMBL6436219 0.80 NPSR1 (0.52) ALDH1A1CNR2HDAC3HDAC1HDAC2
SCHEMBL14424449 0.78 HDAC1 (0.70) ALDH1A1HDAC3HDAC1HDAC2HDAC8
SCHEMBL14003527 0.77 ALDH1A1 (0.61) ALDH1A1CNR2TSHRGAARAB9A
SCHEMBL14285965 0.75 EPHX2 (0.49) ALDH1A1CNR2TSHREPHX1POLB
SCHEMBL11143980 0.74 ALDH1A1 (1.00) ALDH1A1CNR2TSHRGAAMAPT
SCHEMBL17404990 0.74 HDAC1 (0.72) ALDH1A1HDAC3HDAC1HDAC2HDAC8
SCHEMBL11859735 0.73 CYP2C9 (0.72) ALDH1A1HDAC3HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050077648-A1 Solution casting method and polymer film FUJIFILM CORPORATION (JP) 2005-04-14 US disclosed