Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 12/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1593551 | 0.78 | NPY1R (0.62) | NPY1RALDH1A1MAPTKDM4ENPSR1 | |
| SCHEMBL7043079 | 0.74 | NPY1R (0.77) | NPY1RALDH1A1KDM4EMAPK1CRHR1 | |
| SCHEMBL7044146 | 0.74 | NPY1R (0.51) | NPY1RALDH1A1KDM4EMAPK1CRHR1 | |
| Hydrochloric Acid SCHEMBL7042696 | 0.74 | NPY1R (0.76) | NPY1RALDH1A1KDM4EMAPK1CRHR1 | |
| SCHEMBL7157670 | 0.72 | NPY1R (0.84) | NPY1RALDH1A1MAPTKDM4ENPSR1 | |
| SCHEMBL1594098 | 0.70 | NPY1R (0.65) | NPY1RALDH1A1MAPTKDM4ENPSR1 | |
| SCHEMBL1593110 | 0.68 | NPY1R (0.68) | NPY1RALDH1A1MAPTKDM4ENPSR1 | |
| SCHEMBL1593291 | 0.68 | NPY1R (0.47) | NPY1RCRHR1 | |
| SCHEMBL5729567 | 0.68 | NPY1R (0.79) | NPY1RALDH1A1MAPTKDM4ENPSR1 | |
| SCHEMBL5729654 | 0.67 | NPY1R (0.78) | NPY1RALDH1A1MAPTKDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218379-A2 | CERTAIN ALKYLENE DIAMINE-SUBSTITUTED PYRAZOLO 1,5,-a]-1,5-PYRIMIDINES AND PYRAZOLO 1,5-a]-1,3,5-TRIAZINES | NEUROGEN CORPORATION (US) | 2002-07-03 | — | — | EP | claimed |
| WO-2001023387-A2 | CERTAIN ALKYLENE DIAMINE-SUBSTITUTED PYRAZOLO[1,5,-a]-1,5-PYRIMIDINES AND PYRAZOLO[1,5-a]-1,3,5-TRIAZINES | NEUROGEN CORPORATION (US) | 2001-04-05 | — | — | WO | claimed |
| EP-1499277-A4 | MODIFICATION OF FEEDING BEHAVIOR | IMP COLLEGE INNOVATIONS LTD (GB) | 2005-08-31 | — | — | EP | disclosed |
| EP-1499277-A2 | MODIFICATION OF FEEDING BEHAVIOR | Imperial College Innovations Limited (GB) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003026591-A2 | MODIFICATION OF FEEDING BEHAVIOR | IMPERIAL COLLEGE INNOVATIONS LTD. (GB) | 2003-04-03 | — | — | WO | disclosed |