Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 11/20 | 0.41 |
| ▸ | CDK8 | P49336 | 11/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | CDK19 | Q9BWU1 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6437870 | 0.94 | CCNC (0.40) | CCNCCDK8IMPDH2CDK19NAMPT | |
| SCHEMBL6437873 | 0.94 | CCNC (0.40) | CCNCCDK8IMPDH2CDK19NAMPT | |
| SCHEMBL6432546 | 0.88 | PLK1 (0.44) | CCNCCDK8CDK19NAMPTLMNA | |
| SCHEMBL6429437 | 0.87 | CCNC (0.46) | CCNCCDK8CDK19MAOAACHE | |
| SCHEMBL29208304 | 0.85 | CCNC (0.43) | CCNCCDK8CDK19LMNASMN1; SMN2 | |
| SCHEMBL6434501 | 0.85 | CCNC (0.43) | CCNCCDK8CDK19LMNASMN1; SMN2 | |
| SCHEMBL4829431 | 0.83 | CCNC (0.42) | CCNCCDK8IMPDH2CDK19NAMPT | |
| SCHEMBL4829446 | 0.83 | CCNC (0.42) | CCNCCDK8IMPDH2CDK19NAMPT | |
| SCHEMBL4825940 | 0.83 | CCNC (0.40) | CCNCCDK8IMPDH2CDK19NAMPT | |
| SCHEMBL4554192 | 0.82 | MAPT (0.41) | CCNCCDK8CDK19NAMPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556032-A1 | AGENT FOR PREVENTING OR TREATING NEUROPATHY | Takeda Pharmaceutical Company Limited (JP) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004039365-A1 | AGENT FOR PREVENTING OR TREATING NEUROPATHY | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-05-13 | — | — | WO | disclosed |