Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 6/20 | 0.46 |
| ▸ | CDK8 | P49336 | 6/20 | 0.46 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6429433 | 0.93 | CCNC (0.45) | CCNCCDK8CDK19ACHEHDAC1 | |
| SCHEMBL6429439 | 0.93 | CCNC (0.45) | CCNCCDK8CDK19ACHEHDAC1 | |
| SCHEMBL6434501 | 0.90 | CCNC (0.43) | CCNCCDK8CDK19RAB9AEGFR | |
| SCHEMBL6438696 | 0.90 | HTR2A (0.44) | CCNCCDK8CDK19HDAC1HDAC2 | |
| SCHEMBL6431326 | 0.90 | HDAC1 (0.42) | CCNCCDK8CDK19HDAC1HDAC2 | |
| SCHEMBL29208304 | 0.90 | CCNC (0.43) | CCNCCDK8CDK19RAB9AEGFR | |
| SCHEMBL6429585 | 0.90 | HDAC1 (0.46) | ACHEHDAC1HDAC2MEN1MAPT | |
| SCHEMBL6429773 | 0.89 | HTR2A (0.42) | CCNCCDK8CDK19MAOAMAOB | |
| SCHEMBL6437872 | 0.87 | CCNC (0.41) | CCNCCDK8CDK19ACHEMAOA | |
| SCHEMBL6432546 | 0.85 | PLK1 (0.44) | CCNCCDK8CDK19ACHEHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556032-A1 | AGENT FOR PREVENTING OR TREATING NEUROPATHY | Takeda Pharmaceutical Company Limited (JP) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004039365-A1 | AGENT FOR PREVENTING OR TREATING NEUROPATHY | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-05-13 | — | — | WO | disclosed |