Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLA1 | P09884 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6438607 | 1.00 | LMNA (0.45) | LMNAPOLA1ALDH1A1 | |
| SCHEMBL2167108 | 0.88 | LMNA (0.41) | LMNAPOLA1 | |
| SCHEMBL2167111 | 0.88 | LMNA (0.41) | LMNAPOLA1 | |
| SCHEMBL2167271 | 0.88 | LMNA (0.41) | LMNAPOLA1 | |
| SCHEMBL2167274 | 0.88 | LMNA (0.41) | LMNAPOLA1 | |
| SCHEMBL2167105 | 0.88 | LMNA (0.41) | LMNAPOLA1 | |
| SCHEMBL2167340 | 0.83 | LMNA (0.41) | LMNAPOLA1ALDH1A1 | |
| SCHEMBL2168058 | 0.83 | LMNA (0.41) | LMNAPOLA1ALDH1A1 | |
| SCHEMBL2167334 | 0.83 | LMNA (0.41) | LMNAPOLA1ALDH1A1 | |
| SCHEMBL1073412 | 0.82 | LMNA (0.39) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203760-B1 | Method for producing cyclopropanecarboxylates | SUMITOMO CHEMICAL CO (JP) | 2005-04-13 | — | — | EP | disclosed |
| US-6706910-B2 | BY TRANSESTERIFICATION OF A CYCLOPROPANECARBOXYLATE AND A MONOHYDROXY COMPOUND IN THE PRESENCE OF A LITHIUM ALKOXIDE OR LITHIUM ARYLOXIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-03-16 | — | — | US | disclosed |
| EP-1203760-A1 | Method for producing cyclopropanecarboxylates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-05-08 | — | — | EP | disclosed |
| US-20020052525-A1 | Method for producing cyclopropanecarboxylates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020052525-A1 | Method for producing cyclopropanecarboxylates | CYP8B1, SRD5A2, CYP21A2 | LMNA 1815/4885POLA1 2155/4885ALDH1A1 671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.