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Arginine

Arginine

SCHEMBL6438609

CC(C)C[C@H](N)C(=O)O.CC[C@H](C)[C@H](N)C(=O)O.CSCC[C@H](N)C(=O)O.C[C@H](N)C(=O)OC(=O)[C@@H](N)[C@@H](C)O.N=C(N)NCCC[C@H](N)C(=O)O.NC(=O)CC[C@H](N)C(=O)O.NC(=O)C[C@H](N)C(=O)O.NCC(=O)O.NCCCC[C@H](N)C(=O)O.N[C@@H](CC(=O)O)C(=O)O.N[C@@H](CCC(=O)O)C(=O)O.N[C@@H](COC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)O.N[C@@H](CS)C(=O)O.N[C@@H](Cc1c[nH]cn1)C(=O)O.N[C@@H](Cc1ccccc1)C(=O)O.O=C(O)[C@@H]1CCCN1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACE

The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ PTH1R Q03431 10/20 0.41
▸ KEAP1 Q14145 2/20 0.40
▸ GLP1R P43220 7/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Arginine SCHEMBL6482306 0.94 PTH1R (0.40) PTH1RGLP1R
Tryptophan SCHEMBL27661960 0.93 PTH1R (0.44) PTH1RKEAP1GLP1R
Tryptophan SCHEMBL27448344 0.90 GLP1R (0.44) PTH1RGLP1R
Tryptophan SCHEMBL27645885 0.90 GLP1R (0.44) PTH1RGLP1R
Tryptophan SCHEMBL27646591 0.90 GLP1R (0.45) PTH1RGLP1R
Tryptophan SCHEMBL5820703 0.90 PTH1R (0.39) PTH1RGLP1R
Tryptophan SCHEMBL27534250 0.89 GLP1R (0.42) PTH1RGLP1R
Tryptophan SCHEMBL27700472 0.89 GLP1R (0.45) GLP1R
Tryptophan SCHEMBL9152334 0.89 PTH1R (0.42) PTH1RKEAP1GLP1R
Tryptophan SCHEMBL27505901 0.89 GLP1R (0.45) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1562579-A1 THERAPEUTIC DELIVERY OF CARBON MONOXIDE Hemocorm Limited (GB) 2005-08-17 — — EP disclosed
WO-2004045599-A1 THERAPEUTIC DELIVERY OF CARBON MONOXIDE HEMOCORM LIMITED (GB) 2004-06-03 — — WO disclosed