Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.57 |
| ▸ | ITGAV | P06756 | 14/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.42 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.42 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6440629 | 0.83 | ITGB3 (0.56) | ITGB3ITGAVKCNH2HSD17B10BCHE | |
| SCHEMBL6424626 | 0.83 | ITGB3 (0.59) | ITGB3ITGAVKCNH2HSD17B10BCHE | |
| SCHEMBL6440635 | 0.82 | ITGB3 (0.55) | ITGB3ITGAVKCNH2HSD17B10BCHE | |
| SCHEMBL6444230 | 0.81 | ITGB3 (0.68) | ITGB3ITGAVHSD17B10 | |
| SCHEMBL5024060 | 0.80 | ITGB3 (0.73) | ITGB3ITGAV | |
| SCHEMBL5025667 | 0.79 | ITGB3 (0.72) | ITGB3ITGAV | |
| SCHEMBL6424509 | 0.77 | ITGB3 (0.64) | ITGB3ITGAV | |
| SCHEMBL6440900 | 0.77 | ITGB3 (0.49) | ITGB3ITGAVKCNH2HSD17B10BCHE | |
| SCHEMBL5025631 | 0.75 | ITGB3 (0.62) | ITGB3ITGAVKCNH2 | |
| SCHEMBL5025493 | 0.74 | ITGB3 (0.59) | ITGB3ITGAVKCNH2HSD17B10BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286673-B8 | LIGANDS OF INTEGRIN RECEPTORS | ABBOTT GMBH & CO KG (DE) | 2005-07-20 | — | — | EP | disclosed |
| EP-1286673-A2 | LIGANDS OF INTEGRIN RECEPTORS | Basf Aktiengesellschaft (DE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001093840-A2 | LIGANDS OF INTEGRIN RECEPTORS | BASF AG (DE) | 2001-12-13 | — | — | WO | disclosed |