Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 5/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | BCL2 | P10415 | 1/20 | 0.51 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.51 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6436632 | 0.90 | MEN1 (0.57) | MEN1KMT2APOLBTDP1SMN1; SMN2 | |
| SCHEMBL2422491 | 0.90 | MAPT (0.58) | MEN1KMT2APOLBTDP1SMN1; SMN2 | |
| SCHEMBL7894671 | 0.87 | MEN1 (0.58) | MEN1KMT2APOLBTDP1SMN1; SMN2 | |
| SCHEMBL2424858 | 0.86 | MAPK9 (0.61) | MEN1KMT2APOLBTDP1SMN1; SMN2 | |
| SCHEMBL2423054 | 0.85 | MAPK9 (0.59) | MEN1KMT2APOLBTDP1SMN1; SMN2 | |
| SCHEMBL2428129 | 0.81 | MAPK9 (0.56) | MEN1KMT2APOLBTDP1SMN1; SMN2 | |
| SCHEMBL7896117 | 0.81 | ALDH1A1 (0.58) | MEN1KMT2APOLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL7894661 | 0.81 | MEN1 (0.64) | MEN1KMT2APOLBTDP1SMN1; SMN2 | |
| SCHEMBL2421411 | 0.81 | MAPK9 (0.53) | MEN1KMT2APOLBTDP1SMN1; SMN2 | |
| SCHEMBL2423073 | 0.80 | MAPK9 (0.55) | MEN1KMT2APOLBTDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218374-B1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | APPLIED RESEARCH SYSTEMS (AN) | 2005-11-16 | — | — | EP | claimed |