Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LSS | P48449 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6440120 | 0.95 | MAPT (0.54) | MAPTPPARAELANEL3MBTL1LMNA | |
| SCHEMBL6438647 | 0.90 | PPARA (0.66) | MAPTPPARAGAAL3MBTL1LMNA | |
| SCHEMBL6439701 | 0.89 | PPARA (0.54) | MAPTPPARAGAAHDAC8ELANE | |
| SCHEMBL6437795 | 0.88 | MAPT (0.47) | MAPTPPARAELANEL3MBTL1LMNA | |
| SCHEMBL6440953 | 0.86 | HDAC8 (0.45) | MAPTPPARAGAAHDAC8L3MBTL1 | |
| SCHEMBL6440664 | 0.84 | PPARA (0.63) | MAPTPPARAGAAELANEL3MBTL1 | |
| SCHEMBL6438658 | 0.82 | HDAC1 (0.44) | MAPTHDAC8L3MBTL1LMNAMEN1 | |
| SCHEMBL29135410 | 0.81 | HDAC8 (0.49) | GAAHDAC8L3MBTL1HTT | |
| SCHEMBL25810589 | 0.81 | HDAC8 (0.49) | GAAHDAC8L3MBTL1RAB9ALSS | |
| SCHEMBL9729899 | 0.80 | MAPT (0.59) | MAPTPPARAGAAL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506959-A2 | Derivatised molecules for mass spectrometry | OXFORD GENE TECHNOLOGY IP LIMITED (GB) | 2005-02-16 | — | — | EP | disclosed |