Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HRH2 | P25021 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | VNN1 | O95497 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730131 | 0.86 | PPARA (0.69) | MAPTHPGDLMNAMEN1KMT2A | |
| SCHEMBL6440120 | 0.85 | MAPT (0.54) | MAPTHPGDLMNAMEN1KMT2A | |
| SCHEMBL14566050 | 0.85 | MAPT (0.56) | MAPTHPGDLMNAMEN1KMT2A | |
| SCHEMBL11456703 | 0.84 | L3MBTL1 (0.71) | MAPTHPGDLMNAMEN1KMT2A | |
| SCHEMBL1814631 | 0.83 | MAPT (0.62) | MAPTHPGDLMNAMEN1KMT2A | |
| SCHEMBL11233455 | 0.83 | MAPT (0.66) | MAPTHPGDLMNAMEN1KMT2A | |
| SCHEMBL14821465 | 0.82 | PPARA (0.44) | MAPTLMNAKMT2ARAB9APPARA | |
| SCHEMBL14821466 | 0.82 | PPARA (0.44) | MAPTLMNAKMT2ARAB9APPARA | |
| SCHEMBL10428949 | 0.82 | MAPT (0.59) | MAPTHPGDLMNAMEN1KMT2A | |
| SCHEMBL10421733 | 0.81 | ESRRB (0.53) | MAPTHPGDLMNAKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124478-A | ACID-LABILE ANCHOR GROUPS FOR THE SYNTHESIS OF PEPTIDE AMIDES BY A SOLID-PHASE METHOD | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-06-23 | — | — | US | disclosed |