Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 18/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6437537 | 0.88 | MEN1 (0.71) | KCNA3MEN1ALDH1A1KMT2ASLC6A9 | |
| SCHEMBL6438777 | 0.87 | MEN1 (0.72) | KCNA3MEN1ALDH1A1KMT2ASLC6A9 | |
| SCHEMBL13593781 | 0.87 | KCNA3 (0.62) | KCNA3MEN1ALDH1A1KMT2ASLC6A9 | |
| SCHEMBL6439381 | 0.86 | KCNA3 (0.68) | KCNA3MEN1ALDH1A1KMT2ASLC6A9 | |
| SCHEMBL2470583 | 0.85 | MEN1 (0.67) | KCNA3MEN1ALDH1A1KMT2ASLC6A9 | |
| SCHEMBL6440287 | 0.85 | KCNA3 (0.70) | KCNA3MEN1ALDH1A1KMT2ASLC6A9 | |
| SCHEMBL6436136 | 0.85 | MEN1 (0.75) | KCNA3MEN1ALDH1A1KMT2ASLC6A9 | |
| SCHEMBL2471695 | 0.84 | SLC6A9 (0.68) | KCNA3MEN1ALDH1A1KMT2ASLC6A9 | |
| SCHEMBL6435262 | 0.83 | MEN1 (0.72) | KCNA3MEN1ALDH1A1KMT2ASLC6A9 | |
| SCHEMBL2469741 | 0.83 | MEN1 (0.76) | KCNA3MEN1ALDH1A1KMT2ASLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1126849-B1 | HETEROCYCLIC POTASSIUM CHANNEL INHIBITORS | MERCK & CO INC (US) | 2005-03-09 | — | — | EP | disclosed |
| US-6303637-B1 | FOR THERAPY OF AUTOIMMUNE DISEASE, PROPHYLAXIS OF RESISTANCE TO TRANSPLANTATION OR TRANSPLANTATION REJECTION OF ORGANS OR TISSUES; SUPPRESSING IMMUNE SYSTEM | MERCK & CO., INC. | 2001-10-16 | — | — | US | disclosed |