Naphthalene

Naphthalene

SCHEMBL6439633

O=C(O)c1ccc2cc(C(=O)O)ccc2c1.c1ccc2ccccc2c1

nearest known ligand 0.71

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.71
CES1 P23141 1/20 0.71
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
NR1H4 Q96RI1 1/20 0.59
KDM4E B2RXH2 3/20 0.59
PTPN1 P18031 3/20 0.59
TDP1 Q9NUW8 2/20 0.59
HPGD P15428 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
ALDH1A1 P00352 1/20 0.59
EGFR P00533 1/20 0.59
TP53 P04637 1/20 0.59
CYP3A4 P08684 1/20 0.59
MAPT P10636 1/20 0.59
PKM P14618 1/20 0.59
ALOX15 P16050 1/20 0.59
ALOX12 P18054 1/20 0.59
JAK1 P23458 1/20 0.59
MAPK1 P28482 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Beta-Naphtoic Acid SCHEMBL98296 1.00 CES2 (0.71) CES2CES1MEN1KMT2ANR1H4
Beta-Naphtoic Acid SCHEMBL30678321 1.00 CES2 (0.71) CES2CES1MEN1KMT2ANR1H4
Beta-Naphtoic Acid SCHEMBL30678322 1.00 CES2 (0.71) CES2CES1MEN1KMT2ANR1H4
Beta-Naphtoic Acid SCHEMBL29628843 1.00 CES2 (0.71) CES2CES1MEN1KMT2ANR1H4
Beta-Naphtoic Acid SCHEMBL25370444 0.98 CES2 (0.68) CES2CES1MEN1KMT2ANR1H4
Beta-Naphtoic Acid SCHEMBL9180782 0.98 CES2 (0.68) CES2CES1MEN1KMT2ANR1H4
Beta-Naphtoic Acid SCHEMBL10672354 0.98 CES2 (0.68) CES2CES1MEN1KMT2ANR1H4
Beta-Naphtoic Acid SCHEMBL6907286 0.98 CES2 (0.68) CES2CES1MEN1KMT2ANR1H4
Beta-Naphtoic Acid SCHEMBL20484022 0.98 CES2 (0.68) CES2CES1MEN1KMT2ANR1H4
Beta-Naphtoic Acid SCHEMBL1193528 0.98 CES2 (0.68) CES2CES1MEN1KMT2ANR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1212279-B1 PURIFICATION OF AROMATIC DIACIDS MOSSI & GHISOLFI INT SA (LU) 2004-09-22 EP claimed
EP-1212278-B1 A PROCESS FOR SEPARATION OF CRUDE NAPHTHALENE DICARBOXYLIC ACID USING REVERSE OSMOSIS MOSSI & GHISOLFI INT SA (LU) 2005-01-19 EP disclosed
US-6562999-B2 Purifying 2,6-naphthalene dicarboxylic acid produced by disproportionation and recycling byproduct dipotassium salts MOSSI & GHISOLFI OVERSEAS S.A. (LU) 2003-05-13 US disclosed
US-20020123646-A1 Process for separation of crude naphthalene dicarboxylic acid using reverse osmosis MOSSI & GHISOLFI OVERSEAS, S.A. 2002-09-05 US disclosed
EP-1212278-A2 A PROCESS FOR SEPARATION OF CRUDE NAPHTHALENE DICARBOXYLIC ACID USING REVERSE OSMOSIS Mossi & Ghisolfi Overseas S.A. (LU) 2002-06-12 EP disclosed
WO-2001016067-A2 A PROCESS FOR SEPARATION OF CRUDE NAPHTHALENE DICARBOXYLIC ACID USING REVERSE OSMOSIS MOSSI & GHISOLFI OVERSEAS S.A. (IT) 2001-03-08 WO disclosed
US-5919403-A POLYESTERS EASTMAN CHEMICAL COMPANY (US) 1999-07-06 US disclosed
EP-0868488-A1 NAPHTHALENEDICARBOXYLATE CONTAINING POLYESTER BLEND COMPOSITIONS HAVING REDUCED FLUORESCENCE EASTMAN CHEMICAL COMPANY (US) 1998-10-07 EP disclosed
EP-0868465-A1 POLYMERIC FLUORESCENCE QUENCHING COMPOUNDS AND THEIR USE EASTMAN CHEMICAL COMPANY (US) 1998-10-07 EP disclosed
WO-1997023540-A1 POLYMERIC FLUORESCENCE QUENCHING COMPOUNDS AND THEIR USE EASTMAN CHEMICAL COMPANY (US) 1997-07-03 WO disclosed
WO-1997023568-A1 NAPHTHALENEDICARBOXYLATE CONTAINING POLYESTER BLEND COMPOSITIONS HAVING REDUCED FLUORESCENCE EASTMAN CHEMICAL COMPANY (US) 1997-07-03 WO disclosed