SCHEMBL6439664

SCHEMBL6439664

Cc1cc(C)cc(-c2[nH]c3ccc(C(C)(C)C(=O)N4CC5CCC4CC5)cc3c2C(C)CNCCc2ccncc2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GNRHR P30968 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1535425 1.00 GNRHR (1.00) GNRHR
SCHEMBL13692916 0.93 GNRHR (0.87) GNRHR
SCHEMBL1535413 0.89 GNRHR (0.81) GNRHR
SCHEMBL13691354 0.88 GNRHR (0.79) GNRHR
SCHEMBL7542960 0.88 GNRHR (0.79) GNRHR
SCHEMBL7542963 0.88 GNRHR (0.79) GNRHR
SCHEMBL7905285 0.87 GNRHR (1.00) GNRHR
SCHEMBL14421669 0.86 GNRHR (0.75) GNRHR
SCHEMBL4375114 0.86 GNRHR (0.75) GNRHR
SCHEMBL8079311 0.85 GNRHR (0.75) GNRHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1599494-A2 RESTORING FUNCTION TO GONADOTROPIN RELEASING HORMONE RECEPTOR MUTANTS Oregon Health and Science University (US) 2005-11-30 EP disclosed
WO-2004069859-A2 RESTORING FUNCTION TO GONADOTROPIN RELEASING HORMONE RECEPTOR MUTANTS OREGON HEALTH AND SCIENCE UNIVERSITY (US) 2004-08-19 WO disclosed