SCHEMBL7905285

SCHEMBL7905285

Cc1cc(C)cc(-c2[nH]c3ccc(C(C)(C)C(=O)N4C5CCC4CC5)cc3c2C(C)CNCCCCc2ccncc2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GNRHR P30968 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7977280 0.89 GNRHR (0.81) GNRHR
SCHEMBL7977286 0.89 GNRHR (0.81) GNRHR
SCHEMBL7544164 0.88 GNRHR (0.78) GNRHR
SCHEMBL7544172 0.88 GNRHR (0.78) GNRHR
SCHEMBL6985296 0.87 GNRHR (1.00) GNRHR
SCHEMBL1535425 0.87 GNRHR (1.00) GNRHR
SCHEMBL6439664 0.87 GNRHR (1.00) GNRHR
SCHEMBL6983762 0.86 GNRHR (0.78) GNRHR
SCHEMBL7871273 0.86 GNRHR (1.00) GNRHR
SCHEMBL8162514 0.86 GNRHR (1.00) GNRHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6200957-B1 USEFUL FOR TREATMENT OF VARIETY OF SEX-HORMONE RELATED AND OTHER CONDITIONS IN BOTH MEN AND WOMEN MERCK & CO., INC. 2001-03-13 US disclosed