SCHEMBL6439849

SCHEMBL6439849

Cc1c(Cl)c(Cl)c(CO)c(Cl)c1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22402722 0.88
SCHEMBL6439077 0.86 CYP1A2 (0.32)
SCHEMBL522497 0.84 PDXK (0.33)
SCHEMBL306109 0.81 MEN1 (0.35)
SCHEMBL22402720 0.79
SCHEMBL10495956 0.78 HPGD (0.34)
Ethylene Glycol SCHEMBL11692529 0.78 TSHR (0.36)
SCHEMBL560496 0.78 MEN1 (0.33)
SCHEMBL22402731 0.76 DRD4 (0.37)
SCHEMBL11318159 0.74 MEN1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1203760-B1 Method for producing cyclopropanecarboxylates SUMITOMO CHEMICAL CO (JP) 2005-04-13 EP disclosed
US-6706910-B2 BY TRANSESTERIFICATION OF A CYCLOPROPANECARBOXYLATE AND A MONOHYDROXY COMPOUND IN THE PRESENCE OF A LITHIUM ALKOXIDE OR LITHIUM ARYLOXIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-03-16 US disclosed
EP-1203760-A1 Method for producing cyclopropanecarboxylates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-05-08 EP disclosed
US-20020052525-A1 Method for producing cyclopropanecarboxylates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-05-02 US disclosed