Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6436012 | 1.00 | MAPT (0.41) | MAPTLMNACYP3A4CYP17A1NR1I2 | |
| SCHEMBL6446575 | 0.89 | CYP17A1 (0.40) | MAPTLMNACYP3A4CYP17A1NR1I2 | |
| SCHEMBL7198892 | 0.82 | MAPT (0.37) | MAPTLMNACYP3A4CYP17A1NR1I2 | |
| SCHEMBL6443701 | 0.82 | MAPT (0.37) | MAPTLMNACYP3A4CYP17A1NR1I2 | |
| SCHEMBL7195126 | 0.82 | MAPT (0.37) | MAPTLMNACYP3A4CYP17A1NR1I2 | |
| SCHEMBL6445681 | 0.82 | MAPT (0.37) | MAPTLMNACYP3A4CYP17A1NR1I2 | |
| SCHEMBL19961196 | 0.80 | MAPT (0.61) | MAPTLMNACYP3A4CYP17A1NR1I2 | |
| SCHEMBL16144354 | 0.80 | MAPT (0.61) | MAPTLMNACYP3A4CYP17A1NR1I2 | |
| SCHEMBL8624760 | 0.78 | SHBG (0.39) | CYP3A4CYP19A1SHBG | |
| SCHEMBL7195029 | 0.78 | SHBG (0.57) | MAPTLMNACYP3A4NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113354-A1 | Bioavailable prodrugs of androgenic steroids and related method | ROBERTS WILLIAM J (US) | 2005-05-26 | — | — | US | claimed |
| US-20030134830-A1 | Bioavailable prodrugs of androgenic steroids and related method | BIOTEST LABORATORIES, LLC | 2003-07-17 | — | — | US | claimed |
| US-20030134831-A1 | Bioavailable prodrugs of androgenic steroids and related method | BIOTEST LABORATORIES, LLC | 2003-07-17 | — | — | US | disclosed |