Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8848832 | 0.83 | TAAR1 (0.47) | TAAR1IDO1MAOBCTBP2ACHE | |
| SCHEMBL4660551 | 0.80 | IDO1 (0.47) | TAAR1IDO1MAOBCTBP2ACHE | |
| SCHEMBL14363111 | 0.80 | TAAR1 (0.53) | TAAR1IDO1MAOBCTBP2ACHE | |
| SCHEMBL28099898 | 0.79 | MAOB (0.46) | MAOBTRPA1 | |
| SCHEMBL5487172 | 0.76 | CTBP2 (0.50) | TAAR1MAOBCTBP2POLB | |
| SCHEMBL28914536 | 0.76 | TAAR1 (0.45) | TAAR1IDO1MAOBCTBP2GPR84 | |
| SCHEMBL13750029 | 0.75 | TAAR1 (0.51) | TAAR1IDO1CTBP2ACHEGPR84 | |
| SCHEMBL6083918 | 0.75 | TAAR1 (0.50) | TAAR1IDO1MAOBCTBP2ACHE | |
| SCHEMBL1295849 | 0.74 | TAAR1 (0.42) | TAAR1IDO1MAOBCTBP2ACHE | |
| SCHEMBL1295844 | 0.74 | TAAR1 (0.42) | TAAR1IDO1MAOBCTBP2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949230-B1 | PROCESSES FOR PRODUCING ALKENYL-SUBSTITUTED AROMATIC HYDROCARBONS | SUMITOMO CHEMICAL CO (JP) | 2005-07-27 | — | — | EP | disclosed |
| US-6403852-B1 | CATALYTIC ALKENYLATION OF ALKYL-SUBSTITUTED AROMATIC HYDROCARBON HAVING HYDROGEN ATOM AT ALPHA-POSITION OF SIDE CHAIN THEREOF WITH CONJUGATED DIENE | SUMITOMO CHEMICAL CO., LIMITED (JP) | 2002-06-11 | — | — | US | disclosed |
| EP-0949230-A1 | PROCESSES FOR PRODUCING ALKENYL-SUBSTITUTED AROMATIC HYDROCARBONS | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1999-10-13 | — | — | EP | disclosed |