SCHEMBL8848832

SCHEMBL8848832

CC(C)=CCc1cccc(C)c1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.47
IDO1 P14902 2/20 0.46
ACHE P22303 2/20 0.42
MAOB P27338 2/20 0.41
CTBP2 P56545 1/20 0.41
GPR84 Q9NQS5 1/20 0.41
POLB P06746 1/20 0.40
GGPS1 O95749 1/20 0.40
HRH3 Q9Y5N1 1/20 0.40
AKR1C3 P42330 1/20 0.39
AKR1C2 P52895 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP2D6 P10635 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1904000 0.87 GGPS1 (0.47) MAOBGGPS1AKR1C3AKR1C2ALDH1A1
SCHEMBL4660551 0.85 IDO1 (0.47) TAAR1IDO1ACHEMAOBCTBP2
SCHEMBL14363111 0.85 TAAR1 (0.53) TAAR1IDO1ACHEMAOBCTBP2
SCHEMBL6440035 0.83 TAAR1 (0.44) TAAR1IDO1ACHEMAOBCTBP2
SCHEMBL5487172 0.80 CTBP2 (0.50) TAAR1MAOBCTBP2POLBALDH1A1
SCHEMBL27314752 0.80 GGPS1 (0.43) GGPS1AKR1C3AKR1C2ALDH1A1
SCHEMBL2811400 0.80 PRSS1 (0.44) GGPS1AKR1C3AKR1C2
SCHEMBL13750029 0.79 TAAR1 (0.51) TAAR1IDO1ACHECTBP2GPR84
SCHEMBL6083918 0.79 TAAR1 (0.50) TAAR1IDO1ACHEMAOBCTBP2
SCHEMBL13189961 0.78 GGPS1 (0.42) MAOBGGPS1AKR1C3AKR1C2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0594856-B1 PROCESS FOR PRODUCING DIALKYLNAPHTHALENE TEIJIN LTD (JP) 1997-04-02 EP disclosed
US-5365001-A Catalytic cyclization of alkenebenzene in the presence of hydrogen TEIJIN LIMITED (JP) 1994-11-15 US disclosed
EP-0594856-A1 PROCESS FOR PRODUCING DIALKYLNAPHTHALENE TEIJIN LIMITED (JP) 1994-05-04 EP disclosed