Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3480008 | 0.85 | NR1H2 (0.40) | NR1H2 | |
| SCHEMBL22492311 | 0.74 | ADORA1 (0.47) | NR1H2 | |
| SCHEMBL22492346 | 0.74 | ADORA1 (0.50) | NR1H2 | |
| SCHEMBL24209724 | 0.72 | ADORA1 (0.43) | NR1H2 | |
| SCHEMBL2923652 | 0.71 | CCNA2 (0.38) | — | |
| SCHEMBL5720840 | 0.71 | NR1H2 (0.40) | NR1H2 | |
| SCHEMBL30090465 | 0.71 | NR1H2 (0.40) | NR1H2 | |
| SCHEMBL30707227 | 0.69 | NR1H2 (0.39) | NR1H2 | |
| SCHEMBL29723403 | 0.68 | NR1H2 (0.38) | NR1H2 | |
| SCHEMBL24209760 | 0.68 | ADORA1 (0.45) | NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1527074-A1 | BICYCLO-PYRAZOLES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | Pharmacia Italia S.p.A. (IT) | 2005-05-04 | — | — | EP | disclosed |
| WO-2004013144-A1 | BICYCLO-PYRAZOLES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | PHARMACIA ITALIA SPA (IT) | 2004-02-12 | — | — | WO | disclosed |