SCHEMBL6440508

SCHEMBL6440508

CCOC=C(C(=O)c1ccc(F)c(OC)c1SC)C(=O)C1CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6440505 1.00
SCHEMBL8391671 0.83
SCHEMBL6440301 0.82 MEP1B (0.30)
SCHEMBL6440305 0.82 MEP1B (0.30)
SCHEMBL8388430 0.81 MAPT (0.33)
SCHEMBL8309730 0.80
SCHEMBL8309731 0.80
SCHEMBL8489453 0.78 HPGD (0.47)
SCHEMBL8725799 0.77 MAPT (0.32)
SCHEMBL8309793 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1066237-B1 PROCESSES FOR PREPARING INTERMEDIATES BAYER CROPSCIENCE SA (FR) 2005-07-20 EP disclosed
US-6642418-B1 1,3-dione compounds from beta keto esters AVENTIS CROPSCIENCE SA (FR) 2003-11-04 US disclosed
EP-1066237-A2 PROCESSES FOR PREPARING INTERMEDIATES AVENTIS CROPSCIENCE S.A. (FR) 2001-01-10 EP disclosed
WO-1999048851-A2 PROCESSES FOR PREPARING INTERMEDIATES AVENTIS CROPSCIENCE S.A. (FR) 1999-09-30 WO disclosed